Reactome | Release of p-STAT2:p-STAT1 dimer

Schema > Reaction > Entries

category	dissociation
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10261288
displayName	Release of p-STAT2:p-STAT1 dimer
eventOf	[Pathway:R-CFA-909733] Interferon alpha/beta signaling - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-909722] Release of p-STAT2:p-STAT1 dimer - Homo sapiens
input	[Complex:R-CFA-909711] IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Release of p-STAT2:p-STAT1 dimer
output	[Complex:R-CFA-909704] IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2 [plasma membrane] [Complex:R-CFA-909702] p-STAT2:p-STAT1 [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-909722
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CFA-909733] Interferon alpha/beta signaling
(inferredTo)	[Reaction:R-HSA-909722] Release of p-STAT2:p-STAT1 dimer

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