Reactome | NOTCH3 coactivator complex binds HES1 gene promoter

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NOTCH3 coactivator complex binds HES1 gene promoter Show undefined attributes

authored	[InstanceEdit:9021699] Orlic-Milacic, Marija, 2017-09-20
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9013654] Orlic-Milacic, Marija, 2017-07-25
dbId	9013652
displayName	NOTCH3 coactivator complex binds HES1 gene promoter
edited	[InstanceEdit:9027527] Orlic-Milacic, Marija, 2017-11-02
eventOf	[Pathway:R-HSA-9013508] NOTCH3 Intracellular Domain Regulates Transcription - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-9013567] HES1 gene expression is stimulated by NOTCH3 and STAT1 - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:20142] positive regulation of transcription of Notch receptor target
inferredFrom	[Reaction:R-NUL-9013660] Notch3 coactivator complex binds Hes1 gene promoter - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-2197548] HES1 gene [nucleoplasm] [Complex:R-HSA-2248837] NOTCH3 coactivator complex [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	NOTCH3 coactivator complex binds HES1 gene promoter
output	[Complex:R-HSA-9013653] NOTCH3 coactivator complex:HES1 gene [nucleoplasm]
precedingEvent	[Reaction:R-HSA-9013631] NICD3 binds RBPJ and MAML in the nucleus - Homo sapiens
releaseDate	2017-12-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9027525] Haw, Robin, 2017-10-30
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9013652
summation	[Summation:9013724] NOTCH3 coactivator complex, composed of at least NICD3 (NOTC...

Referrals

(hasEvent)	[Pathway:R-HSA-9013508] NOTCH3 Intracellular Domain Regulates Transcription
(precedingEvent)	[BlackBoxEvent:R-HSA-9013567] HES1 gene expression is stimulated by NOTCH3 and STAT1
(inferredTo)	[Reaction:R-NUL-9013660] Notch3 coactivator complex binds Hes1 gene promoter

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