Reactome | MPST transfers sulfur from 3MPYR to HCN to form HSCN

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MPST transfers sulfur from 3MPYR to HCN to form HSCN Show undefined attributes

authored	[InstanceEdit:9013472] Jassal, Bijay, 2017-07-25
catalystActivity	[CatalystActivity:9012723] sulfurtransferase activity of MPST [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:9013472] Jassal, Bijay, 2017-07-25
dbId	9013471
displayName	MPST transfers sulfur from 3MPYR to HCN to form HSCN
edited	[InstanceEdit:9013472] Jassal, Bijay, 2017-07-25
eventOf	[Pathway:R-HSA-1614558] Degradation of cysteine and homocysteine - Homo sapiens
input	[SimpleEntity:R-ALL-9012592] 3MPYR [mitochondrial matrix] [SimpleEntity:R-ALL-9013199] HCN [mitochondrial matrix]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9013202] Enzymatic conversion of cyanide to thiocyanate [LiteratureReference:9013205] A partial exploration of the potential energy surfaces of SCN and HSCN: implications for the enzyme-mediated detoxification of cyanide [LiteratureReference:9013474] In-vitro mercaptopyruvate sulfurtransferase species comparison in humans and common laboratory animals
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	MPST transfers sulfur from 3MPYR to HCN to form HSCN
orthologousEvent	[Reaction:R-GGA-9013471] MPST transfers sulfur from 3MPYR to HCN to form HSCN - Gallus gallus [Reaction:R-PFA-9013471] MPST transfers sulfur from 3MPYR to HCN to form HSCN - Plasmodium falciparum [Reaction:R-SCE-9013471] MPST transfers sulfur from 3MPYR to HCN to form HSCN - Saccharomyces cerevisiae [Reaction:R-SPO-9013471] MPST transfers sulfur from 3MPYR to HCN to form HSCN - Schizosaccharomyces pombe [Reaction:R-DDI-9013471] MPST transfers sulfur from 3MPYR to HCN to form HSCN - Dictyostelium discoideum [Reaction:R-CEL-9013471] MPST transfers sulfur from 3MPYR to HCN to form HSCN - Caenorhabditis elegans [Reaction:R-XTR-9013471] MPST transfers sulfur from 3MPYR to HCN to form HSCN - Xenopus tropicalis [Reaction:R-DRE-9013471] MPST transfers sulfur from 3MPYR to HCN to form HSCN - Danio rerio [Reaction:R-SSC-9013471] MPST transfers sulfur from 3MPYR to HCN to form HSCN - Sus scrofa [Reaction:R-BTA-9013471] MPST transfers sulfur from 3MPYR to HCN to form HSCN - Bos taurus [Reaction:R-CFA-9013471] MPST transfers sulfur from 3MPYR to HCN to form HSCN - Canis familiaris [Reaction:R-RNO-9013471] MPST transfers sulfur from 3MPYR to HCN to form HSCN - Rattus norvegicus [Reaction:R-MMU-9013471] MPST transfers sulfur from 3MPYR to HCN to form HSCN - Mus musculus
output	[SimpleEntity:R-ALL-9013191] HSCN [mitochondrial matrix] [SimpleEntity:R-ALL-113557] PYR [mitochondrial matrix]
precedingEvent	[Reaction:R-HSA-9012597] GOT2 dimer transfers amino group from L-Cys to 2OG to form 3MPYR and Glu - Homo sapiens [Reaction:R-HSA-9035484] MPST and TXN2 enable the synthesis of disulfanide from CysS248-MPST - Homo sapiens
releaseDate	2018-03-21
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9034676] Patterson, Steven, Belani, Kumar, 2018-01-10
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9013471
summation	[Summation:9013469] Cyanide is a potent metabolic poison which binds to and inhi...

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(hasEvent)

[Pathway:R-HSA-1614558] Degradation of cysteine and homocysteine

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