CBX5 gene expression is inhibited by E2F6

Stable Identifier
R-HSA-9007646
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
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CBX5 gene expression is inhibited by E2F6
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Transcription of the CBX5 (HP1alpha) gene is inhibited by binding of E2F6 to the CBX5 promoter (Oberley et al. 2003).

Literature References
PubMed ID Title Journal Year
12909625 E2F6 negatively regulates BRCA1 in human cancer cells without methylation of histone H3 on lysine 9

Oberley, MJ, Inman, DR, Farnham, PJ

J. Biol. Chem. 2003
Participants
Input
Output
Participates
as an event of
This event is regulated
Negatively by
Regulator
E2F6:(TFDP1,TFDP2):CBX5 gene [nucleoplasm] (Homo sapiens)
Active Unit
E2F6:(TFDP1,TFDP2) [nucleoplasm]
Authored
Orlic-Milacic, M  (2017-06-01)
Reviewed
Herlihy, A  (2017-05-12)
Created
Orlic-Milacic, M  (2017-05-31)
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