Reactome | ERBB4s80:STAT5A binds CSN2 gene promoter

Schema > Reaction > Entries

ERBB4s80:STAT5A binds CSN2 gene promoter Show undefined attributes

authored	[InstanceEdit:1972351] Orlic-Milacic, M, 2011-11-04 [InstanceEdit:9638819] Stern, David F, 2019-02-21
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:8954220] Orlic-Milacic, Marija, 2017-01-05
dbId	8954224
displayName	ERBB4s80:STAT5A binds CSN2 gene promoter
edited	[InstanceEdit:1972361] Matthews, L, 2011-11-07 [InstanceEdit:9638824] Orlic-Milacic, Marija, 2019-03-05
eventOf	[Pathway:R-HSA-1251985] Nuclear signaling by ERBB4 - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-1254290] CSN2 gene expression is stimulated by ERBB4s80:STAT5A - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-8954222] CSN2 gene [nucleoplasm] [Complex:R-HSA-1254288] ERBB4s80:p-Y694-STAT5A [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1254286] The ERBB4/HER4 receptor tyrosine kinase regulates gene expression by functioning as a STAT5A nuclear chaperone [LiteratureReference:1254297] Prolactin and ErbB4/HER4 signaling interact via Janus kinase 2 to induce mammary epithelial cell gene expression differentiation
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	ERBB4s80:STAT5A binds CSN2 gene promoter
output	[Complex:R-HSA-8954223] ERBB4s80:p-Y694-STAT5A:CSN2 gene [nucleoplasm]
precedingEvent	[BlackBoxEvent:R-HSA-1254285] ERBB4s80:STAT5A complex translocates to the nucleus - Homo sapiens
releaseDate	2011-12-06
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:1979910] Harris, RC, 2011-11-11 [InstanceEdit:1979909] Zeng, F, 2011-11-11 [InstanceEdit:2104982] Earp HS, 3rd, 2012-02-20 [InstanceEdit:2104979] Misior, AM, 2012-02-20
revised	[InstanceEdit:2104982] Earp HS, 3rd, 2012-02-20 [InstanceEdit:2104979] Misior, AM, 2012-02-20
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-8954224
summation	[Summation:8954225] ERBB4s80:STAT5A complex binds to the promoter of the CSN2 ge...

Referrals

(hasEvent)	[Pathway:R-HSA-1251985] Nuclear signaling by ERBB4
(precedingEvent)	[BlackBoxEvent:R-HSA-1254290] CSN2 gene expression is stimulated by ERBB4s80:STAT5A

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