Reactome | ERBB4s80:STAT5A complex translocates to the nucleus

Schema > BlackBoxEvent > Entries

ERBB4s80:STAT5A complex translocates to the nucleus Show undefined attributes

authored	[InstanceEdit:1972351] Orlic-Milacic, M, 2011-11-04 [InstanceEdit:9638819] Stern, David F, 2019-02-21
category	omitted
compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:1254294] Orlic-Milacic, Marija, 2011-04-28
dbId	1254285
displayName	ERBB4s80:STAT5A complex translocates to the nucleus
edited	[InstanceEdit:1972361] Matthews, L, 2011-11-07 [InstanceEdit:9638824] Orlic-Milacic, Marija, 2019-03-05
eventOf	[Pathway:R-HSA-1251985] Nuclear signaling by ERBB4 - Homo sapiens
followingEvent	[Reaction:R-HSA-8954224] ERBB4s80:STAT5A binds CSN2 gene promoter - Homo sapiens
input	[Complex:R-HSA-1254284] ERBB4s80:p-Y694-STAT5A [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1254286] The ERBB4/HER4 receptor tyrosine kinase regulates gene expression by functioning as a STAT5A nuclear chaperone [LiteratureReference:1254297] Prolactin and ErbB4/HER4 signaling interact via Janus kinase 2 to induce mammary epithelial cell gene expression differentiation
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	ERBB4s80:STAT5A complex translocates to the nucleus
orthologousEvent	[BlackBoxEvent:R-CFA-1254285] ERBB4s80:STAT5A complex translocates to the nucleus - Canis familiaris [BlackBoxEvent:R-CEL-1254285] ERBB4s80:STAT5A complex translocates to the nucleus - Caenorhabditis elegans [BlackBoxEvent:R-DME-1254285] ERBB4s80:STAT5A complex translocates to the nucleus - Drosophila melanogaster [BlackBoxEvent:R-GGA-1254285] ERBB4s80:STAT5A complex translocates to the nucleus - Gallus gallus [BlackBoxEvent:R-XTR-1254285] ERBB4s80:STAT5A complex translocates to the nucleus - Xenopus tropicalis [BlackBoxEvent:R-DRE-1254285] ERBB4s80:STAT5A complex translocates to the nucleus - Danio rerio [BlackBoxEvent:R-SSC-1254285] ERBB4s80:STAT5A complex translocates to the nucleus - Sus scrofa [BlackBoxEvent:R-BTA-1254285] ERBB4s80:STAT5A complex translocates to the nucleus - Bos taurus [BlackBoxEvent:R-RNO-1254285] ERBB4s80:STAT5A complex translocates to the nucleus - Rattus norvegicus [BlackBoxEvent:R-MMU-1254285] ERBB4s80:STAT5A complex translocates to the nucleus - Mus musculus
output	[Complex:R-HSA-1254288] ERBB4s80:p-Y694-STAT5A [nucleoplasm]
precedingEvent	[Reaction:R-HSA-1254291] ERBB4s80 binds STAT5A - Homo sapiens
releaseDate	2011-12-06
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:1979910] Harris, RC, 2011-11-11 [InstanceEdit:1979909] Zeng, F, 2011-11-11 [InstanceEdit:2104982] Earp HS, 3rd, 2012-02-20 [InstanceEdit:2104979] Misior, AM, 2012-02-20
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-1254285
summation	[Summation:1254280] Formation of cytosolic complex of ERBB4s80 and STAT5A promot...

Referrals

(hasEvent)	[Pathway:R-HSA-1251985] Nuclear signaling by ERBB4
(precedingEvent)	[Reaction:R-HSA-8954224] ERBB4s80:STAT5A binds CSN2 gene promoter