Reactome | Negative regulation by 'EP300 [nucleoplasm]'

Schema > NegativeRegulation > Entries

created	[InstanceEdit:8952416] Orlic-Milacic, Marija, 2016-12-14
dbId	8952420
displayName	Negative regulation by 'EP300 [nucleoplasm]'
modified	[InstanceEdit:9608020] Wu, G, 2018-05-08
regulatedEntity	[Reaction:R-HSA-8952419] SMURFs ubiquitinate RUNX3 - Homo sapiens
regulator	[EntityWithAccessionedSequence:R-HSA-381325] EP300 [nucleoplasm]
schemaClass	NegativeRegulation
stId	R-HSA-8952420

(regulation)	[RegulationReference:9641748] Negative regulation by 'EP300 [nucleoplasm]' Transforming growth factor-beta stimulates p300-dependent RUNX3 acetylation, which inhibits ubiquitination-mediated degradation
(regulatedBy)	[Reaction:R-HSA-8952419] SMURFs ubiquitinate RUNX3

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