Reactome | RUNX2 and SP7 bind the UCMA gene promoter

Schema > Reaction > Entries

RUNX2 and SP7 bind the UCMA gene promoter Show undefined attributes

authored	[InstanceEdit:8939830] Orlic-Milacic, Marija, 2016-09-21
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:8939855] Orlic-Milacic, Marija, 2016-09-21
dbId	8939852
displayName	RUNX2 and SP7 bind the UCMA gene promoter
edited	[InstanceEdit:9015316] Orlic-Milacic, Marija, 2017-08-09
eventOf	[Pathway:R-HSA-8940973] RUNX2 regulates osteoblast differentiation - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-8939870] UCMA gene expression is stimulated by RUNX2 and SP7 - Homo sapiens
inferredFrom	[Reaction:R-MMU-8939880] Runx2:Cbfb and Sp7 bind the Ucma gene promoter - Mus musculus
input	[Complex:R-HSA-8865420] RUNX2:CBFB [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-8939843] SP7 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-8939861] UCMA gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:8939864] Ucma, a direct transcriptional target of Runx2 and Osterix, promotes osteoblast differentiation and nodule formation
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	RUNX2 and SP7 bind the UCMA gene promoter
output	[Complex:R-HSA-8939856] RUNX2:CBFB:SP7:UCMA gene [nucleoplasm]
precedingEvent	[Reaction:R-HSA-8865425] RUNX2 binds CBFB - Homo sapiens
releaseDate	2017-09-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9015314] Ducy, Patricia, 2017-08-04
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-8939852
summation	[Summation:8939863] Based on mouse studies, RUNX2, presumably associated with CB...

Referrals

(precedingEvent)	[BlackBoxEvent:R-HSA-8939870] UCMA gene expression is stimulated by RUNX2 and SP7
(hasEvent)	[Pathway:R-HSA-8940973] RUNX2 regulates osteoblast differentiation
(inferredTo)	[Reaction:R-MMU-8939880] Runx2:Cbfb and Sp7 bind the Ucma gene promoter

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