Reactome | IL3 gene transcription is stimulated by RUNX1 and ELF1

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IL3 gene transcription is stimulated by RUNX1 and ELF1 Show undefined attributes

authored	[InstanceEdit:8938982] Orlic-Milacic, Marija, 2016-09-14
category	omitted
compartment	[Compartment:7660] nucleoplasm [Compartment:984] extracellular region
created	[InstanceEdit:8938982] Orlic-Milacic, Marija, 2016-09-14
dbId	8938981
displayName	IL3 gene transcription is stimulated by RUNX1 and ELF1
edited	[InstanceEdit:9005626] Orlic-Milacic, Marija, 2017-05-09
eventOf	[Pathway:R-HSA-8939247] RUNX1 regulates transcription of genes involved in interleukin signaling - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-8938941] IL3 gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:8938917] Functional and physical interactions between AML1 proteins and an ETS protein, MEF: implications for the pathogenesis of t(8;21)-positive leukemias
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	IL3 gene transcription is stimulated by RUNX1 and ELF1
output	[EntityWithAccessionedSequence:R-HSA-450059] IL3 [extracellular region]
precedingEvent	[Reaction:R-HSA-8938938] RUNX1 and ELF1 bind the IL3 gene promoter - Homo sapiens
regulatedBy	[PositiveGeneExpressionRegulation:R-HSA-8938980] Positive gene expression regulation by 'RUNX1:CBFB:ELF1:IL3 gene [nucleoplasm]'
regulationReference	[RegulationReference:9642463] Positive gene expression regulation by 'RUNX1:CBFB:ELF1:IL3 gene [nucleoplasm]' Functional and physical interactions between AML1 proteins and an ETS protein, MEF: implications for the pathogenesis of t(8;21)-positive leukemias
releaseDate	2017-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9005627] Ito, Yoshiaki, 2016-12-20 [InstanceEdit:9005628] Chuang, Linda Shyue Huey, 2016-12-20
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-8938981
summation	[Summation:8938979] Binding of the RUNX1:CBFB complex associated with ELF1, an E...

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[Pathway:R-HSA-8939247] RUNX1 regulates transcription of genes involved in interleukin signaling

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