Reactome | RUNX1 and ELF1 bind the IL3 gene promoter

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RUNX1 and ELF1 bind the IL3 gene promoter Show undefined attributes

authored	[InstanceEdit:8938982] Orlic-Milacic, Marija, 2016-09-14
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:8938939] Orlic-Milacic, Marija, 2016-09-14
dbId	8938938
displayName	RUNX1 and ELF1 bind the IL3 gene promoter
edited	[InstanceEdit:9005626] Orlic-Milacic, Marija, 2017-05-09
eventOf	[Pathway:R-HSA-8939247] RUNX1 regulates transcription of genes involved in interleukin signaling - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-8938981] IL3 gene transcription is stimulated by RUNX1 and ELF1 - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-8938941] IL3 gene [nucleoplasm] [Complex:R-HSA-8938916] RUNX1:CBFB:ELF1 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:8938917] Functional and physical interactions between AML1 proteins and an ETS protein, MEF: implications for the pathogenesis of t(8;21)-positive leukemias
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	RUNX1 and ELF1 bind the IL3 gene promoter
output	[Complex:R-HSA-8938942] RUNX1:CBFB:ELF1:IL3 gene [nucleoplasm]
precedingEvent	[Reaction:R-HSA-8938913] RUNX1 binds ELF1 - Homo sapiens
releaseDate	2017-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9005627] Ito, Yoshiaki, 2016-12-20 [InstanceEdit:9005628] Chuang, Linda Shyue Huey, 2016-12-20
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-8938938
summation	[Summation:8938937] RUNX1 (AML1) and ELF1 (MEF) bind to adjacent RUNX1- and ETS-...

Referrals

(precedingEvent)	[BlackBoxEvent:R-HSA-8938981] IL3 gene transcription is stimulated by RUNX1 and ELF1
(hasEvent)	[Pathway:R-HSA-8939247] RUNX1 regulates transcription of genes involved in interleukin signaling

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