Reactome | RUNX2:CBFB:p-Y-YAP1 binds the BGLAP gene promoter

Schema > Reaction > Entries

RUNX2:CBFB:p-Y-YAP1 binds the BGLAP gene promoter Show undefined attributes

authored	[InstanceEdit:8937870] Orlic-Milacic, Marija, 2016-09-07
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:8937870] Orlic-Milacic, Marija, 2016-09-07
dbId	8937869
displayName	RUNX2:CBFB:p-Y-YAP1 binds the BGLAP gene promoter
edited	[InstanceEdit:9015316] Orlic-Milacic, Marija, 2017-08-09
eventOf	[Pathway:R-HSA-8940973] RUNX2 regulates osteoblast differentiation - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-8877922] BGLAP gene expression is stimulated by RUNX2, WWTR1 and RB1 and inhibited by AR, YAP1 and ZNF521 - Homo sapiens
inferredFrom	[Reaction:R-RNO-8937949] Runx2:Cbfb:p-Y-Yap1 binds the Bglap gene promoter - Rattus norvegicus
input	[EntityWithAccessionedSequence:R-HSA-8877914] BGLAP gene [nucleoplasm] [Complex:R-HSA-8937863] RUNX2:CBFB:p-Y-YAP1 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:8937826] Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	RUNX2:CBFB:p-Y-YAP1 binds the BGLAP gene promoter
output	[Complex:R-HSA-8937871] RUNX2:CBFB:p-Y-YAP1:BGLAP gene [nucleoplasm]
precedingEvent	[Reaction:R-HSA-8937864] RUNX2 binds tyrosine phosphorylated YAP1 - Homo sapiens
releaseDate	2017-09-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9015314] Ducy, Patricia, 2017-08-04
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-8937869
summation	[Summation:8937868] Based on studies in rat, the complex of RUNX2, presumably as...

Referrals

(precedingEvent)	[BlackBoxEvent:R-HSA-8877922] BGLAP gene expression is stimulated by RUNX2, WWTR1 and RB1 and inhibited by AR, YAP1 and ZNF521
(hasEvent)	[Pathway:R-HSA-8940973] RUNX2 regulates osteoblast differentiation
(inferredTo)	[Reaction:R-RNO-8937949] Runx2:Cbfb:p-Y-Yap1 binds the Bglap gene promoter

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