Reactome | HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane]

Schema > Complex > Entries

HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-8875574] HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:(DOCK7) [plasma membrane] - Homo sapiens [Complex:R-HSA-8875665] HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:GGA3:ARF6:GTP [recycling endosome membrane] - Homo sapiens
consumedByEvent	[BlackBoxEvent:R-HSA-8875576] CRK,CRKL recruits RAC1 GEF to activated MET - Homo sapiens [Reaction:R-HSA-8875558] RAPGEF1 binds CRK,CRKL - Homo sapiens [BlackBoxEvent:R-HSA-8875661] GGA3 associates with activated MET receptor - Homo sapiens
created	[InstanceEdit:8875539] Orlic-Milacic, Marija, 2016-06-07
dbId	8875548
displayName	HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane]
hasComponent	[DefinedSet:R-HSA-381945] CRK, CRKL [cytosol] [DefinedSet:R-HSA-8851943] HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane]
inDisease	false
includedLocation	[Compartment:70101] cytosol
inferredTo	[Complex:R-MMU-8875548] HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] - Mus musculus [Complex:R-RNO-8875548] HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] - Rattus norvegicus [Complex:R-CFA-8875548] HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] - Canis familiaris [Complex:R-BTA-8875548] HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] - Bos taurus [Complex:R-SSC-8875548] HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] - Sus scrofa [Complex:R-DRE-8875548] HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] - Danio rerio [Complex:R-XTR-8875548] HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] - Xenopus tropicalis [Complex:R-GGA-8875548] HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] - Gallus gallus
isChimeric	false
maxDepth	7
modified	[InstanceEdit:8879177] Wu, G, 2016-07-15
name	HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL
producedByEvent	[Reaction:R-HSA-8875540] GAB1 recruits CRK,CRKL to MET - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-8875548

Referrals

(hasComponent)	[Complex:R-HSA-8875665] HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:GGA3:ARF6:GTP [recycling endosome membrane] [Complex:R-HSA-8875561] HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:RAPGEF1 [plasma membrane] [Complex:R-HSA-8875574] HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:(DOCK7) [plasma membrane]
(input)	[BlackBoxEvent:R-HSA-8875661] GGA3 associates with activated MET receptor [Reaction:R-HSA-8875558] RAPGEF1 binds CRK,CRKL [BlackBoxEvent:R-HSA-8875576] CRK,CRKL recruits RAC1 GEF to activated MET
(output)	[Reaction:R-HSA-8875540] GAB1 recruits CRK,CRKL to MET

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