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Schema
>
Complex
>
Entries
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:GGA3:ARF6:GTP [recycling endosome membrane]
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compartment
[Compartment:262783] recycling endosome membrane
consumedByEvent
[BlackBoxEvent:R-HSA-8875659] RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane - Homo sapiens
created
[InstanceEdit:8875667] Orlic-Milacic, Marija, 2016-06-08
dbId
8875665
displayName
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:GGA3:ARF6:GTP [recycling endosome membrane]
hasComponent
[Complex:R-HSA-2193115] ARF6:GTP [recycling endosome membrane]
[EntityWithAccessionedSequence:R-HSA-8875655] GGA3 [recycling endosome membrane]
[Complex:R-HSA-8875548] HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane]
inDisease
false
includedLocation
[Compartment:70101] cytosol
[Compartment:876] plasma membrane
inferredTo
[Complex:R-MMU-8875665] HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:GGA3:ARF6:GTP [recycling endosome membrane] - Mus musculus
[Complex:R-RNO-8875665] HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:GGA3:ARF6:GTP [recycling endosome membrane] - Rattus norvegicus
[Complex:R-CFA-8875665] HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:GGA3:ARF6:GTP [recycling endosome membrane] - Canis familiaris
[Complex:R-BTA-8875665] HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:GGA3:ARF6:GTP [recycling endosome membrane] - Bos taurus
[Complex:R-SSC-8875665] HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:GGA3:ARF6:GTP [recycling endosome membrane] - Sus scrofa
[Complex:R-DRE-8875665] HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:GGA3:ARF6:GTP [recycling endosome membrane] - Danio rerio
[Complex:R-XTR-8875665] HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:GGA3:ARF6:GTP [recycling endosome membrane] - Xenopus tropicalis
[Complex:R-GGA-8875665] HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:GGA3:ARF6:GTP [recycling endosome membrane] - Gallus gallus
isChimeric
false
literatureReference
[LiteratureReference:8875664] GGA3 functions as a switch to promote Met receptor recycling, essential for sustained ERK and cell migration
maxDepth
8
modified
[InstanceEdit:8879177] Wu, G, 2016-07-15
name
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:GGA3:ARF6:GTP
producedByEvent
[BlackBoxEvent:R-HSA-8875661] GGA3 associates with activated MET receptor - Homo sapiens
schemaClass
Complex
species
[Species:48887] Homo sapiens
stId
R-HSA-8875665
Referrals
(input)
[BlackBoxEvent:R-HSA-8875659] RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane
(output)
[BlackBoxEvent:R-HSA-8875661] GGA3 associates with activated MET receptor
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