Reactome | NPM1:TFAP2A homodimer [nucleoplasm]

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-8869540] NPM1:TFAP2A homodimer:MYBL2 gene [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-8869549] TFPA2A homodimer and NPM1 bind the MYBL2 gene promoter - Homo sapiens [Reaction:R-HSA-8869542] TFPA2A homodimer and NPM1 bind the HSPD1 gene promoter - Homo sapiens [Reaction:R-HSA-8869543] TFPA2A homodimer and NPM1 bind the NOP2 gene promoter - Homo sapiens
created	[InstanceEdit:8869556] Orlic-Milacic, Marija, 2016-05-05
dbId	8869555
displayName	NPM1:TFAP2A homodimer [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-HSA-606320] NPM1 [nucleoplasm] [Complex:R-HSA-8864382] TFAP2A homodimer [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-MMU-8869555] NPM1:TFAP2A homodimer [nucleoplasm] - Mus musculus [Complex:R-RNO-8869555] NPM1:TFAP2A homodimer [nucleoplasm] - Rattus norvegicus [Complex:R-CFA-8869555] NPM1:TFAP2A homodimer [nucleoplasm] - Canis familiaris [Complex:R-BTA-8869555] NPM1:TFAP2A homodimer [nucleoplasm] - Bos taurus [Complex:R-SSC-8869555] NPM1:TFAP2A homodimer [nucleoplasm] - Sus scrofa [Complex:R-XTR-8869555] NPM1:TFAP2A homodimer [nucleoplasm] - Xenopus tropicalis [Complex:R-GGA-8869555] NPM1:TFAP2A homodimer [nucleoplasm] - Gallus gallus [Complex:R-DME-8869555] NPM1:TFAP2A homodimer [nucleoplasm] - Drosophila melanogaster
isChimeric	false
literatureReference	[LiteratureReference:8869487] Nucleophosmin acts as a novel AP2alpha-binding transcriptional corepressor during cell differentiation
maxDepth	3
modified	[InstanceEdit:8871616] Weiser, JD
name	NPM1:TFAP2A homodimer Nucleophosmin:AP-2 alpha homodimer
producedByEvent	[Reaction:R-HSA-8869568] NPM1 binds TFAP2A homodimer - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-8869555

(activeUnit)	[NegativeGeneExpressionRegulation:R-HSA-8869563] Negative gene expression regulation by 'NPM1:TFAP2A homodimer:NOP2 gene [nucleoplasm]' [NegativeGeneExpressionRegulation:R-HSA-8869562] Negative gene expression regulation by 'NPM1:TFAP2A homodimer:MYBL2 gene [nucleoplasm]' [NegativeGeneExpressionRegulation:R-HSA-8869557] Negative gene expression regulation by 'NPM1:TFAP2A homodimer:HSPD1 gene [nucleoplasm]'
(input)	[Reaction:R-HSA-8869549] TFPA2A homodimer and NPM1 bind the MYBL2 gene promoter [Reaction:R-HSA-8869542] TFPA2A homodimer and NPM1 bind the HSPD1 gene promoter [Reaction:R-HSA-8869543] TFPA2A homodimer and NPM1 bind the NOP2 gene promoter
(hasComponent)	[Complex:R-HSA-8869540] NPM1:TFAP2A homodimer:MYBL2 gene [nucleoplasm] [Complex:R-HSA-8869545] NPM1:TFAP2A homodimer:HSPD1 gene [nucleoplasm] [Complex:R-HSA-8869544] NPM1:TFAP2A homodimer:NOP2 gene [nucleoplasm]
(output)	[Reaction:R-HSA-8869568] NPM1 binds TFAP2A homodimer

NPM1:TFAP2A homodimer [nucleoplasm] Show undefined attributes

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