Reactome | TFPA2A homodimer and NPM1 bind the NOP2 gene promoter

Schema > Reaction > Entries

TFPA2A homodimer and NPM1 bind the NOP2 gene promoter Show undefined attributes

authored	[InstanceEdit:8864334] Orlic-Milacic, Marija, 2016-03-14
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:8869551] Orlic-Milacic, Marija, 2016-05-05
dbId	8869543
displayName	TFPA2A homodimer and NPM1 bind the NOP2 gene promoter
edited	[InstanceEdit:8864334] Orlic-Milacic, Marija, 2016-03-14
eventOf	[Pathway:R-HSA-8869496] TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-8869560] The NOP2 gene expression is repressed by the complex of NPM1 and TFAP2A homodimer - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-8869515] NOP2 gene [nucleoplasm] [Complex:R-HSA-8869555] NPM1:TFAP2A homodimer [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:8869487] Nucleophosmin acts as a novel AP2alpha-binding transcriptional corepressor during cell differentiation
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	TFPA2A homodimer and NPM1 bind the NOP2 gene promoter
output	[Complex:R-HSA-8869544] NPM1:TFAP2A homodimer:NOP2 gene [nucleoplasm]
precedingEvent	[Reaction:R-HSA-8869568] NPM1 binds TFAP2A homodimer - Homo sapiens
releaseDate	2016-06-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8869464] Zarelli, Valeria E, 2016-05-04 [InstanceEdit:8869466] Dawid, Igor B, 2016-05-04
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-8869543
summation	[Summation:8869546] In response to retinoic acid treatment, TFAP2A (AP-2 alpha) ...

Referrals

(precedingEvent)	[BlackBoxEvent:R-HSA-8869560] The NOP2 gene expression is repressed by the complex of NPM1 and TFAP2A homodimer
(hasEvent)	[Pathway:R-HSA-8869496] TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation

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