Reactome | TFAP2A homodimer [nucleoplasm]

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TFAP2A homodimer [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-8869555] NPM1:TFAP2A homodimer [nucleoplasm] - Homo sapiens [Complex:R-HSA-9907107] MITF-M dimer:TFAP2A:IRF4 gene [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-8869568] NPM1 binds TFAP2A homodimer - Homo sapiens [Reaction:R-HSA-8864737] TFAP2A homodimer binds the VEGFA gene promoter - Homo sapiens [Reaction:R-HSA-8864989] TFAP2A homodimer binds the TGFA gene promoter - Homo sapiens [Reaction:R-HSA-8865244] TFAP2A homodimer binds CDKN1A (p21) gene - Homo sapiens [Reaction:R-HSA-8869580] DEK binds TFAP2A homodimers - Homo sapiens [Reaction:R-HSA-9768288] RB1 and TFAP2A bind CDH1 gene promoter - Homo sapiens [Reaction:R-HSA-9907144] MITF-M dimer and TFAP2A bind intronic elements in the IRF4 gene - Homo sapiens
created	[InstanceEdit:8864388] Orlic-Milacic, Marija, 2016-03-14
dbId	8864382
displayName	TFAP2A homodimer [nucleoplasm]
hasComponent	2 × [EntityWithAccessionedSequence:R-HSA-8864280] TFAP2A [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-MMU-8864382] TFAP2A homodimer [nucleoplasm] - Mus musculus [Complex:R-RNO-8864382] TFAP2A homodimer [nucleoplasm] - Rattus norvegicus [Complex:R-CFA-8864382] TFAP2A homodimer [nucleoplasm] - Canis familiaris [Complex:R-BTA-8864382] TFAP2A homodimer [nucleoplasm] - Bos taurus [Complex:R-SSC-8864382] TFAP2A homodimer [nucleoplasm] - Sus scrofa [Complex:R-XTR-8864382] TFAP2A homodimer [nucleoplasm] - Xenopus tropicalis [Complex:R-GGA-8864382] TFAP2A homodimer [nucleoplasm] - Gallus gallus [Complex:R-DME-8864283] TFAP2 homo- and heterodimers [nucleoplasm] - Drosophila melanogaster [Complex:R-CEL-8864382] TFAP2A homodimer [nucleoplasm] - Caenorhabditis elegans
isChimeric	false
maxDepth	2
memberOf	[CandidateSet:R-HSA-8864685] TFAP2A,(TFAP2B) homodimers [nucleoplasm] - Homo sapiens
modified	[InstanceEdit:8871616] Weiser, JD
name	TFAP2A homodimer AP-2 alpha homodimer
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-8864382

Referrals

(input)	[Reaction:R-HSA-9907144] MITF-M dimer and TFAP2A bind intronic elements in the IRF4 gene [Reaction:R-HSA-8869568] NPM1 binds TFAP2A homodimer [Reaction:R-HSA-8864737] TFAP2A homodimer binds the VEGFA gene promoter [Reaction:R-HSA-8864989] TFAP2A homodimer binds the TGFA gene promoter [Reaction:R-HSA-8865244] TFAP2A homodimer binds CDKN1A (p21) gene [Reaction:R-HSA-8869580] DEK binds TFAP2A homodimers [Reaction:R-HSA-9768288] RB1 and TFAP2A bind CDH1 gene promoter
(hasComponent)	[Complex:R-HSA-9907107] MITF-M dimer:TFAP2A:IRF4 gene [nucleoplasm] [Complex:R-HSA-8869555] NPM1:TFAP2A homodimer [nucleoplasm] [Complex:R-HSA-8864742] TFAP2A homodimer:VEGFA Gene [nucleoplasm] [Complex:R-HSA-8864985] TFAP2A homodimer:TGFA gene [nucleoplasm] [Complex:R-HSA-8865245] TFAP2A homodimer:CDKN1A gene [nucleoplasm] [Complex:R-HSA-8869593] DEK:TFAP2A homodimer [nucleoplasm] [Complex:R-HSA-9794242] RB1:TFAP2A homodimer:CDH1 gene [nucleoplasm]
(activeUnit)	[PositiveGeneExpressionRegulation:9907127] Positive gene expression regulation by 'MITF-M dimer:TFAP2A:IRF4 gene [nucleoplasm]' [NegativeGeneExpressionRegulation:R-HSA-8864939] Negative gene expression regulation by 'TFAP2A homodimer:VEGFA Gene [nucleoplasm]' [PositiveGeneExpressionRegulation:R-HSA-8864998] Positive gene expression regulation by 'TFAP2A homodimer:TGFA gene [nucleoplasm]' [PositiveGeneExpressionRegulation:R-HSA-8865258] Positive gene expression regulation by 'TFAP2A homodimer:CDKN1A gene [nucleoplasm]' [PositiveGeneExpressionRegulation:9794241] Positive gene expression regulation by 'RB1:TFAP2A homodimer:CDH1 gene [nucleoplasm]'
(hasMember)	[CandidateSet:R-HSA-8864685] TFAP2A,(TFAP2B) homodimers [nucleoplasm] [DefinedSet:R-HSA-8864379] TFAP2A,TFAP2C homodimers [nucleoplasm]

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