Reactome | AGFG1 binds VAMP7

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AGFG1 binds VAMP7 Show undefined attributes

authored	[InstanceEdit:8870660] Rothfels, Karen, 2016-05-10
category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:8863719] Rothfels, Karen, 2016-03-09
dbId	8863718
displayName	AGFG1 binds VAMP7
edited	[InstanceEdit:8870660] Rothfels, Karen, 2016-05-10
eventOf	[Pathway:R-HSA-8856825] Cargo recognition for clathrin-mediated endocytosis - Homo sapiens
followingEvent	[Reaction:R-HSA-8867756] CLASP proteins and cargo are recruited to the nascent clathrin-coated pit - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-8863714] AGFG1 [cytosol] [EntityWithAccessionedSequence:R-HSA-376361] VAMP7 [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:8863706] Role of HRB in clathrin-dependent endocytosis [LiteratureReference:8863695] Molecular basis for the sorting of the SNARE VAMP7 into endocytic clathrin-coated vesicles by the ArfGAP Hrb [LiteratureReference:8863711] The eps15 homology (EH) domain-based interaction between eps15 and hrb connects the molecular machinery of endocytosis to that of nucleocytosolic transport [LiteratureReference:1011589] Binding specificity and in vivo targets of the EH domain, a novel protein-protein interaction module [LiteratureReference:8863700] Role of the AP2 beta-appendage hub in recruiting partners for clathrin-coated vesicle assembly [LiteratureReference:8870875] Distinct and separable activities of the endocytic clathrin-coat components Fcho1/2 and AP-2 in developmental patterning
maxDepth	1
modified	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
name	AGFG1 binds VAMP7
orthologousEvent	[Reaction:R-DME-8863718] AGFG1 binds VAMP7 - Drosophila melanogaster [Reaction:R-GGA-8863718] AGFG1 binds VAMP7 - Gallus gallus [Reaction:R-XTR-8863718] AGFG1 binds VAMP7 - Xenopus tropicalis [Reaction:R-DRE-8863718] AGFG1 binds VAMP7 - Danio rerio [Reaction:R-CFA-8863718] AGFG1 binds VAMP7 - Canis familiaris [Reaction:R-RNO-8863718] AGFG1 binds VAMP7 - Rattus norvegicus
output	[Complex:R-HSA-8863716] AGFG1:VAMP7 [plasma membrane]
releaseDate	2016-06-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8870617] Antonescu, Costin N, 2016-05-10
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-8863718
summation	[Summation:8863720] AGFG1, also known as HRB (HIV-1 Rev-binding), is a clathrin ...

Referrals

(hasEvent)	[Pathway:R-HSA-8856825] Cargo recognition for clathrin-mediated endocytosis
(precedingEvent)	[Reaction:R-HSA-8867756] CLASP proteins and cargo are recruited to the nascent clathrin-coated pit

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