Reactome | Glucagon:GCGR mediates GTP-GDP exchange

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Glucagon:GCGR mediates GTP-GDP exchange Show undefined attributes

authored	[InstanceEdit:166004] Gopinathrao, G, 2005-08-12 11:14:59
catalystActivity	[CatalystActivity:163619] guanyl-nucleotide exchange factor activity of GCGR:GCG(53-81) [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:825630] D'Eustachio, P, 2010-05-26
dbId	825631
deleted	[Deleted:790198] Deletion of instance: 163624
displayName	Glucagon:GCGR mediates GTP-GDP exchange
edited	[InstanceEdit:825632] D'Eustachio, P, 2010-05-26
eventOf	[Pathway:R-HSA-163359] Glucagon signaling in metabolic regulation - Homo sapiens
followingEvent	[Reaction:R-HSA-163617] G alpha (s) activates adenylate cyclase - Homo sapiens
input	[Complex:R-HSA-164384] G-protein with G(s) alpha:GDP [plasma membrane] [SimpleEntity:R-ALL-29438] GTP [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:8984217] Structure of the human glucagon class B G-protein-coupled receptor
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Glucagon:GCGR mediates GTP-GDP exchange
output	[Complex:R-HSA-164358] G alpha (s):GTP [plasma membrane] [Complex:R-HSA-164386] G-beta:G-gamma dimer [plasma membrane] [SimpleEntity:R-ALL-29420] GDP [cytosol]
precedingEvent	[Reaction:R-HSA-163625] Glucagon binds to Glucagon receptor - Homo sapiens
releaseDate	2010-06-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:798935] D'Eustachio, P, 2010-05-25
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-825631
summation	[Summation:178805] The G(s)alpha G-beta G-gamma complex bound to glucagon, in t...
updateTrackers	[UpdateTracker:9781427] Update Tracker - [Reaction:825631] Glucagon:GCGR mediates GTP-GDP exchange - v61:[addLiteratureReference, modifyText] [UpdateTracker:9789754] Update Tracker - [Reaction:825631] Glucagon:GCGR mediates GTP-GDP exchange - v37:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9781427] Update Tracker - [Reaction:825631] Glucagon:GCGR mediates GTP-GDP exchange - v61:[addLiteratureReference, modifyText] [UpdateTracker:9789754] Update Tracker - [Reaction:825631] Glucagon:GCGR mediates GTP-GDP exchange - v37:[modifyText]
(replacementInstances)	[Deleted:790198] Deletion of instance: 163624
(hasEvent)	[Pathway:R-HSA-163359] Glucagon signaling in metabolic regulation
(precedingEvent)	[Reaction:R-HSA-163617] G alpha (s) activates adenylate cyclase

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