Reactome | G alpha (s):GTP [plasma membrane]

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G alpha (s):GTP [plasma membrane] Show undefined attributes

catalystActivities	[CatalystActivity:164372] GTPase activity of G alpha (s):GTP [plasma membrane] [CatalystActivity:9857009] adenylate cyclase activator activity of G alpha (s):GTP [plasma membrane]
compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-422306] ADCY5,6,8:G-alpha(s):GTP [plasma membrane] - Homo sapiens [Complex:R-HSA-422311] GLP-1:GLP-1R:Heterotrimeric G(s):GTP [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-381704] G(s):GTP activates Adenylyl cyclase - Homo sapiens [Reaction:R-HSA-8964278] G protein alpha (s):GTP binds SRC - Homo sapiens [Reaction:R-HSA-164381] G alpha (s) auto-inactivates by hydrolysing GTP to GDP - Homo sapiens [Reaction:R-HSA-163617] G alpha (s) activates adenylate cyclase - Homo sapiens
created	[InstanceEdit:164336] Gopinathrao, G, 2005-05-18 22:14:39
dbId	164358
displayName	G alpha (s):GTP [plasma membrane]
hasComponent	[CandidateSet:R-HSA-8873941] GNAS [plasma membrane] [SimpleEntity:R-ALL-29438] GTP [cytosol]
inDisease	false
includedLocation	[Compartment:70101] cytosol
inferredTo	[Complex:R-MMU-164358] G alpha (s):GTP [plasma membrane] - Mus musculus [Complex:R-RNO-164358] G alpha (s):GTP [plasma membrane] - Rattus norvegicus [Complex:R-CFA-164358] G alpha (s):GTP [plasma membrane] - Canis familiaris [Complex:R-BTA-164358] G alpha (s):GTP [plasma membrane] - Bos taurus [Complex:R-DRE-164358] G alpha (s):GTP [plasma membrane] - Danio rerio [Complex:R-XTR-164358] G alpha (s):GTP [plasma membrane] - Xenopus tropicalis [Complex:R-GGA-164358] G alpha (s):GTP [plasma membrane] - Gallus gallus [Complex:R-CEL-164358] G alpha (s):GTP [plasma membrane] - Caenorhabditis elegans
maxDepth	3
modified	[InstanceEdit:9026067] Jupe, Steve, 2017-10-17
name	G alpha (s):GTP Gs:GTP
positivelyRegulates	[PositiveRegulation:R-HSA-5610769] Positive regulation by 'G alpha (s):GTP [plasma membrane]'
producedByEvent	[Reaction:R-HSA-8964287] G alpha (s):GTP:SRC dissociates - Homo sapiens [Reaction:R-HSA-422320] Heterotrimeric G(s) complex dissociates - Homo sapiens [Reaction:R-HSA-825631] Glucagon:GCGR mediates GTP-GDP exchange - Homo sapiens [Reaction:R-HSA-9660819] ADORA2B:Ade-Rib:GsGTP dissociates - Homo sapiens [Reaction:R-HSA-744886] The Ligand:GPCR:Gs complex dissociates - Homo sapiens [Reaction:R-HSA-9861293] ADM:CALCRL:RAMP2:G-alpha(s):GTP:G-beta:G-gamma dissociates - Homo sapiens [Reaction:R-HSA-9036308] ESTG-stimulated dissociation of GPER:heterotrimeric G-protein (s) complex - Homo sapiens [Reaction:R-HSA-392874] Dissociation of the Prostacyclin receptor:Gs complex - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-164358
updateTrackers	[UpdateTracker:9868023] Update Tracker - [Complex:164358] G alpha (s):GTP [plasma membrane] - v28:[modifyName] [UpdateTracker:9869168] Update Tracker - [Complex:164358] G alpha (s):GTP [plasma membrane] - v33:[add_removeHasComponent] [UpdateTracker:9896748] Update Tracker - [Complex:164358] G alpha (s):GTP [plasma membrane] - v60:[add_removeHasComponent] [UpdateTracker:9894830] Update Tracker - [Complex:164358] G alpha (s):GTP [plasma membrane] - v58:[add_removeHasComponent] [UpdateTracker:9898281] Update Tracker - [Complex:164358] G alpha (s):GTP [plasma membrane] - v63:[modifyName, updateContainedComponent] [UpdateTracker:9897823] Update Tracker - [Complex:164358] G alpha (s):GTP [plasma membrane] - v62:[add_removeHasComponent]

Referrals

(updatedInstance)	[UpdateTracker:9868023] Update Tracker - [Complex:164358] G alpha (s):GTP [plasma membrane] - v28:[modifyName] [UpdateTracker:9869168] Update Tracker - [Complex:164358] G alpha (s):GTP [plasma membrane] - v33:[add_removeHasComponent] [UpdateTracker:9896748] Update Tracker - [Complex:164358] G alpha (s):GTP [plasma membrane] - v60:[add_removeHasComponent] [UpdateTracker:9894830] Update Tracker - [Complex:164358] G alpha (s):GTP [plasma membrane] - v58:[add_removeHasComponent] [UpdateTracker:9898281] Update Tracker - [Complex:164358] G alpha (s):GTP [plasma membrane] - v63:[modifyName, updateContainedComponent] [UpdateTracker:9897823] Update Tracker - [Complex:164358] G alpha (s):GTP [plasma membrane] - v62:[add_removeHasComponent]
(input)	[Reaction:R-HSA-381704] G(s):GTP activates Adenylyl cyclase [Reaction:R-HSA-8964278] G protein alpha (s):GTP binds SRC [Reaction:R-HSA-164381] G alpha (s) auto-inactivates by hydrolysing GTP to GDP [Reaction:R-HSA-163617] G alpha (s) activates adenylate cyclase
(hasComponent)	[Complex:R-HSA-422306] ADCY5,6,8:G-alpha(s):GTP [plasma membrane] [Complex:R-HSA-8964279] G alpha (s):GTP:p-Y419-SRC [plasma membrane] [Complex:R-HSA-8964281] G alpha (s):GTP:SRC [plasma membrane] [Complex:R-HSA-422311] GLP-1:GLP-1R:Heterotrimeric G(s):GTP [plasma membrane] [Complex:R-HSA-422322] G-alpha(s):GTP:G-beta:G-gamma [plasma membrane] [Complex:R-HSA-163622] G alpha (s):GTP:Adenylate cyclase [plasma membrane] [Complex:R-HSA-392844] Heterotrimeric G-protein Gs (active) [plasma membrane]
(output)	[Reaction:R-HSA-8964287] G alpha (s):GTP:SRC dissociates [Reaction:R-HSA-9036308] ESTG-stimulated dissociation of GPER:heterotrimeric G-protein (s) complex [Reaction:R-HSA-9861293] ADM:CALCRL:RAMP2:G-alpha(s):GTP:G-beta:G-gamma dissociates [Reaction:R-HSA-422320] Heterotrimeric G(s) complex dissociates [Reaction:R-HSA-825631] Glucagon:GCGR mediates GTP-GDP exchange [Reaction:R-HSA-9660819] ADORA2B:Ade-Rib:GsGTP dissociates [Reaction:R-HSA-392874] Dissociation of the Prostacyclin receptor:Gs complex [Reaction:R-HSA-744886] The Ligand:GPCR:Gs complex dissociates
(activeUnit)	[CatalystActivity:8964227] protein tyrosine kinase activity of G alpha (s):GTP:SRC [plasma membrane]
(physicalEntity)	[CatalystActivity:164372] GTPase activity of G alpha (s):GTP [plasma membrane] [CatalystActivity:9857009] adenylate cyclase activator activity of G alpha (s):GTP [plasma membrane]
(regulator)	[PositiveRegulation:R-HSA-5610769] Positive regulation by 'G alpha (s):GTP [plasma membrane]'

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