Reactome | Methylation of GMP-cap by RNA Methyltransferase

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Methylation of GMP-cap by RNA Methyltransferase Show undefined attributes

authored	[InstanceEdit:77054] Buratowski, S, 2003-10-15 15:18:41
catalystActivity	[CatalystActivity:72082] mRNA (guanine-N7-)-methyltransferase activity of Capping complex (with freed 5'- GMP) [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:77054] Buratowski, S, 2003-10-15 15:18:41
dbId	77090
displayName	Methylation of GMP-cap by RNA Methyltransferase
eventOf	[Pathway:R-HSA-72086] mRNA Capping - Homo sapiens
figure	[Figure:77487] /figures/Cap1c.jpg
followingEvent	[Reaction:R-HSA-77095] Recognition and binding of the mRNA cap by the cap-binding complex - Homo sapiens
input	[SimpleEntity:R-ALL-77087] AdoMet [nucleoplasm] [Complex:R-HSA-77067] Capping complex (with freed 5'- GMP) [nucleoplasm]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:77483] Cloning and characterization of three human cDNAs encoding mRNA (guanine-7-)-methyltransferase, an mRNA cap methylase.
modified	[InstanceEdit:10901498] Wright, Adam, 2024-03-08
name	Methylation of GMP-cap by RNA Methyltransferase
orthologousEvent	[Reaction:R-SCE-77090] Methylation of GMP-cap by RNA Methyltransferase - Saccharomyces cerevisiae [Reaction:R-SPO-77090] Methylation of GMP-cap by RNA Methyltransferase - Schizosaccharomyces pombe [Reaction:R-DDI-77090] Methylation of GMP-cap by RNA Methyltransferase - Dictyostelium discoideum [Reaction:R-CEL-77090] Methylation of GMP-cap by RNA Methyltransferase - Caenorhabditis elegans [Reaction:R-DME-77090] Methylation of GMP-cap by RNA Methyltransferase - Drosophila melanogaster [Reaction:R-SSC-77090] Methylation of GMP-cap by RNA Methyltransferase - Sus scrofa [Reaction:R-BTA-77090] Methylation of GMP-cap by RNA Methyltransferase - Bos taurus [Reaction:R-CFA-77090] Methylation of GMP-cap by RNA Methyltransferase - Canis familiaris [Reaction:R-RNO-77090] Methylation of GMP-cap by RNA Methyltransferase - Rattus norvegicus [Reaction:R-MMU-77090] Methylation of GMP-cap by RNA Methyltransferase - Mus musculus
output	[SimpleEntity:R-ALL-77502] AdoHcy [nucleoplasm] [Complex:R-HSA-113403] mRNA capping factors [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-3009372] p-SUPT5H [nucleoplasm] [Complex:R-HSA-113405] RNA Polymerase II (phosphorylated):TFIIF:capped pre-mRNA [nucleoplasm] [Complex:R-HSA-109634] TFIIH [nucleoplasm]
precedingEvent	[Reaction:R-HSA-77085] Dissociation of transcript with 5'-GMP from GT - Homo sapiens
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-77090
summation	[Summation:77091] In the final step of the capping reaction, the methyltransfe...

Referrals

(hasEvent)	[Pathway:R-HSA-72086] mRNA Capping
(precedingEvent)	[Reaction:R-HSA-77095] Recognition and binding of the mRNA cap by the cap-binding complex