Reactome | Methylation of GMP-cap by RNA Methyltransferase

Schema > Reaction > Entries

Methylation of GMP-cap by RNA Methyltransferase Show undefined attributes

catalystActivity	[CatalystActivity:10339084] mRNA 5'-cap (guanine-N7-)-methyltransferase activity of Capping complex (with freed 5'- GMP) [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10339086
displayName	Methylation of GMP-cap by RNA Methyltransferase
eventOf	[Pathway:R-BTA-72086] mRNA Capping - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-BTA-77095] Recognition and binding of the mRNA cap by the cap-binding complex - Bos taurus
inferredFrom	[Reaction:R-HSA-77090] Methylation of GMP-cap by RNA Methyltransferase - Homo sapiens
input	[SimpleEntity:R-ALL-77087] AdoMet [nucleoplasm] [Complex:R-BTA-77067] Capping complex (with freed 5'- GMP) [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Methylation of GMP-cap by RNA Methyltransferase
output	[SimpleEntity:R-ALL-77502] AdoHcy [nucleoplasm] [Complex:R-BTA-113403] mRNA capping factors [nucleoplasm] [EntityWithAccessionedSequence:R-BTA-3009372] phospho-SUPT5H [nucleoplasm] [Complex:R-BTA-113405] RNA Polymerase II (phosphorylated):TFIIF:capped pre-mRNA [nucleoplasm] [Complex:R-BTA-109634] TFIIH [nucleoplasm]
precedingEvent	[Reaction:R-BTA-77085] Dissociation of transcript with 5'-GMP from GT - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-77090
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-72086] mRNA Capping
(precedingEvent)	[Reaction:R-BTA-77095] Recognition and binding of the mRNA cap by the cap-binding complex
(inferredTo)	[Reaction:R-HSA-77090] Methylation of GMP-cap by RNA Methyltransferase

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