Reactome | (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1)

Schema > Reaction > Entries

(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) Show undefined attributes

catalystActivity	[CatalystActivity:73495] nucleoside monophosphate kinase activity of CMPK1, AK1 [cytosol]
catalystActivityReference	[CatalystActivityReference:9643747] nucleoside monophosphate kinase activity of CMPK1, AK1 [cytosol] Characterization of human UMP/CMP kinase and its phosphorylation of D- and L-form deoxycytidine analogue monophosphates.
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:75119] D'Eustachio, P, 2003-08-25 12:00:00
crossReference	[DatabaseIdentifier:12668061] RHEA:24402 [DatabaseIdentifier:9975905] RHEA:25096 [DatabaseIdentifier:9975900] RHEA:11602 [DatabaseIdentifier:9975906] RHEA:24402
dbId	75125
deleted	[Deleted:500015] Deletion of instance: 110107 [Deleted:500011] Deletion of instances: 75123, 75120
displayName	(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1)
eventOf	[Pathway:R-HSA-499943] Interconversion of nucleotide di- and triphosphates - Homo sapiens
followingEvent	[Reaction:R-HSA-73596] dCMP + H2O => dUMP + NH4+ - Homo sapiens
input	[DefinedSet:R-ALL-500006] (d)CDP, UDP [cytosol] [SimpleEntity:R-ALL-29370] ADP [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:74569] Characterization of human UMP/CMP kinase and its phosphorylation of D- and L-form deoxycytidine analogue monophosphates. [LiteratureReference:110112] Kinetics and equilibria of pyrimidine nucleoside monophosphate kinase from human erythrocytes
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) dCDP + ADP => dCMP + ATP CDP + ADP => CMP + ATP UDP + ADP => UMP + ATP
orthologousEvent	[Reaction:R-MMU-75125] (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) - Mus musculus [Reaction:R-PFA-75125] (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) - Plasmodium falciparum [Reaction:R-SCE-75125] (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) - Saccharomyces cerevisiae [Reaction:R-SPO-75125] (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) - Schizosaccharomyces pombe [Reaction:R-DDI-75125] (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) - Dictyostelium discoideum [Reaction:R-CEL-75125] (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) - Caenorhabditis elegans [Reaction:R-DME-75125] (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) - Drosophila melanogaster [Reaction:R-GGA-75125] (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) - Gallus gallus [Reaction:R-XTR-75125] (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) - Xenopus tropicalis [Reaction:R-DRE-75125] (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) - Danio rerio [Reaction:R-SSC-75125] (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) - Sus scrofa [Reaction:R-BTA-75125] (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) - Bos taurus [Reaction:R-CFA-75125] (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) - Canis familiaris [Reaction:R-RNO-75125] (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) - Rattus norvegicus
output	[DefinedSet:R-ALL-500009] (d)CMP, UMP [cytosol] [SimpleEntity:R-ALL-113592] ATP [cytosol]
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:504064] D'Eustachio, P, 2010-02-05
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-75125
summation	[Summation:500008] Cytosolic UMP-CMP kinase (CMPK1) catalyzes the reversible re...
updateTrackers	[UpdateTracker:9790824] Update Tracker - [Reaction:75125] (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) - v32:[add_removeInput, add_removeOutput, add_removeSummation]

Referrals

(updatedInstance)	[UpdateTracker:9790824] Update Tracker - [Reaction:75125] (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) - v32:[add_removeInput, add_removeOutput, add_removeSummation]
(replacementInstances)	[Deleted:500015] Deletion of instance: 110107 [Deleted:500011] Deletion of instances: 75123, 75120
(hasEvent)	[Pathway:R-HSA-499943] Interconversion of nucleotide di- and triphosphates
(precedingEvent)	[Reaction:R-HSA-73596] dCMP + H2O => dUMP + NH4+
(reverseReaction)	[Reaction:R-HSA-73548] (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1)

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