Reactome | SLC35A3 exchanges UDP-GlcNAc for UMP

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SLC35A3 exchanges UDP-GlcNAc for UMP Show undefined attributes

authored	[InstanceEdit:741453] Jassal, Bijay, 2010-05-14
catalystActivity	[CatalystActivity:741455] UDP-N-acetylglucosamine transmembrane transporter activity of SLC35A3 [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen [Compartment:70101] cytosol
created	[InstanceEdit:741453] Jassal, Bijay, 2010-05-14
crossReference	[DatabaseIdentifier:12668075] RHEA:72695
dbId	741450
diseaseReaction	[FailedReaction:R-HSA-5653622] Defective SLC35A3 does not exchange UDP-GlcNAc for UMP - Homo sapiens
displayName	SLC35A3 exchanges UDP-GlcNAc for UMP
edited	[InstanceEdit:741453] Jassal, Bijay, 2010-05-14
eventOf	[Pathway:R-HSA-727802] Transport of nucleotide sugars - Homo sapiens
followingEvent	[Reaction:R-HSA-2022851] EXT1:EXT2 transfers GlcNAc to the heparan chain - Homo sapiens [Reaction:R-HSA-2025724] B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG - Homo sapiens [Reaction:R-HSA-9953259] EXTL3 dimer transfers GlcNAc to the GAG linker - Homo sapiens
input	[SimpleEntity:R-ALL-162756] UDP-GlcNAc [cytosol] [SimpleEntity:R-ALL-735698] UMP [Golgi lumen]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:741451] Molecular cloning and functional expression of the human Golgi UDP-N-acetylglucosamine transporter
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	SLC35A3 exchanges UDP-GlcNAc for UMP
orthologousEvent	[Reaction:R-BTA-741450] SLC35A3 exchanges UDP-GlcNAc for UMP - Bos taurus [Reaction:R-PFA-741450] SLC35A3 exchanges UDP-GlcNAc for UMP - Plasmodium falciparum [Reaction:R-SPO-741450] SLC35A3 exchanges UDP-GlcNAc for UMP - Schizosaccharomyces pombe [Reaction:R-CEL-741450] SLC35A3 exchanges UDP-GlcNAc for UMP - Caenorhabditis elegans [Reaction:R-GGA-741450] SLC35A3 exchanges UDP-GlcNAc for UMP - Gallus gallus [Reaction:R-XTR-741450] SLC35A3 exchanges UDP-GlcNAc for UMP - Xenopus tropicalis [Reaction:R-DRE-741450] SLC35A3 exchanges UDP-GlcNAc for UMP - Danio rerio [Reaction:R-SSC-741450] SLC35A3 exchanges UDP-GlcNAc for UMP - Sus scrofa [Reaction:R-CFA-741450] SLC35A3 exchanges UDP-GlcNAc for UMP - Canis familiaris [Reaction:R-RNO-741450] SLC35A3 exchanges UDP-GlcNAc for UMP - Rattus norvegicus [Reaction:R-MMU-741450] SLC35A3 exchanges UDP-GlcNAc for UMP - Mus musculus
output	[SimpleEntity:R-ALL-914003] UDP-GlcNAc [Golgi lumen] [SimpleEntity:R-ALL-109402] UMP [cytosol]
releaseDate	2010-06-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:706449] He, L, 2010-05-10
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-741450
summation	[Summation:741445] The human gene SLC35A3 encodes a UDP-GlcNAc transporter (Ish...
updateTrackers	[UpdateTracker:9785550] Update Tracker - [Reaction:741450] SLC35A3 exchanges UDP-GlcNAc for UMP - v52:[modifyText] [UpdateTracker:9789170] Update Tracker - [Reaction:741450] SLC35A3 exchanges UDP-GlcNAc for UMP - v38:[add_removeOutput] [UpdateTracker:9787089] Update Tracker - [Reaction:741450] SLC35A3 exchanges UDP-GlcNAc for UMP - v46:[add_removeInput]

Referrals

(updatedInstance)	[UpdateTracker:9785550] Update Tracker - [Reaction:741450] SLC35A3 exchanges UDP-GlcNAc for UMP - v52:[modifyText] [UpdateTracker:9789170] Update Tracker - [Reaction:741450] SLC35A3 exchanges UDP-GlcNAc for UMP - v38:[add_removeOutput] [UpdateTracker:9787089] Update Tracker - [Reaction:741450] SLC35A3 exchanges UDP-GlcNAc for UMP - v46:[add_removeInput]
(normalReaction)	[FailedReaction:R-HSA-5653622] Defective SLC35A3 does not exchange UDP-GlcNAc for UMP
(hasEvent)	[Pathway:R-HSA-727802] Transport of nucleotide sugars
(precedingEvent)	[Reaction:R-HSA-2025724] B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG [Reaction:R-HSA-2022851] EXT1:EXT2 transfers GlcNAc to the heparan chain [Reaction:R-HSA-9953259] EXTL3 dimer transfers GlcNAc to the GAG linker

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