SLC35A3 exchanges UDP-GlcNAc for UMP

Stable Identifier
R-HSA-741450
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Golgi membrane, Golgi lumen, cytosol
ReviewStatus
5/5
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SLC35A3 exchanges UDP-GlcNAc for UMP
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The human gene SLC35A3 encodes a UDP-GlcNAc transporter (Ishida et al. 1999). It is ubiquitously expressed and resides on the Golgi membrane where it transports UDP- N-acetylglucosamine (GlcNAc) into the Golgi lumen in exchange for UMP.
Literature References
PubMed ID Title Journal Year
10393322 Molecular cloning and functional expression of the human Golgi UDP-N-acetylglucosamine transporter

Ishida, N, Kawakita, M, Yoshioka, S, Takeuchi, M, Chiba, Y

J Biochem 1999
Participants
Input
Output
Participates
as an event of
Catalyst Activity

UDP-N-acetylglucosamine transmembrane transporter activity of SLC35A3 [Golgi membrane]

Physical Entity
SLC35A3 [Golgi membrane] (Homo sapiens)
Activity
UDP-N-acetylglucosamine transmembrane transporter activity (GO:0005462)
Orthologous Events
SLC35A3 exchanges UDP-GlcNAc for UMP (Bos taurus)
SLC35A3 exchanges UDP-GlcNAc for UMP (Caenorhabditis elegans)
SLC35A3 exchanges UDP-GlcNAc for UMP (Canis familiaris)
SLC35A3 exchanges UDP-GlcNAc for UMP (Danio rerio)
SLC35A3 exchanges UDP-GlcNAc for UMP (Gallus gallus)
SLC35A3 exchanges UDP-GlcNAc for UMP (Mus musculus)
SLC35A3 exchanges UDP-GlcNAc for UMP (Rattus norvegicus)
SLC35A3 exchanges UDP-GlcNAc for UMP (Schizosaccharomyces pombe)
SLC35A3 exchanges UDP-GlcNAc for UMP (Sus scrofa)
SLC35A3 exchanges UDP-GlcNAc for UMP (Xenopus tropicalis)
Cross References
Rhea
Authored
Jassal, B  (2010-05-14)
Reviewed
He, L  (2010-05-10)
Created
Jassal, B  (2010-05-14)
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