Reactome | SLC35A3 exchanges UDP-GlcNAc for UMP

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SLC35A3 exchanges UDP-GlcNAc for UMP Show undefined attributes

catalystActivity	[CatalystActivity:10942285] UDP-N-acetylglucosamine transmembrane transporter activity of SLC35A3 [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen [Compartment:70101] cytosol
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10942287
displayName	SLC35A3 exchanges UDP-GlcNAc for UMP
eventOf	[Pathway:R-CEL-727802] Transport of nucleotide sugars - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CEL-9953259] EXTL3 dimer transfers GlcNAc to the GAG linker - Caenorhabditis elegans
inferredFrom	[Reaction:R-HSA-741450] SLC35A3 exchanges UDP-GlcNAc for UMP - Homo sapiens
input	[SimpleEntity:R-ALL-162756] UDP-GlcNAc [cytosol] [SimpleEntity:R-ALL-735698] UMP [Golgi lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	SLC35A3 exchanges UDP-GlcNAc for UMP
output	[SimpleEntity:R-ALL-914003] UDP-GlcNAc [Golgi lumen] [SimpleEntity:R-ALL-109402] UMP [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-741450
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-727802] Transport of nucleotide sugars
(precedingEvent)	[Reaction:R-CEL-9953259] EXTL3 dimer transfers GlcNAc to the GAG linker
(inferredTo)	[Reaction:R-HSA-741450] SLC35A3 exchanges UDP-GlcNAc for UMP

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