Reactome | EIF4B [cytosol]

Schema > EntityWithAccessionedSequence > Entries

EIF4B [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-9822333] deadenylated mRNP regulated by BTG4 [cytosol] - Homo sapiens [Complex:R-HSA-429977] Translatable mRNA Complex [cytosol] - Homo sapiens [Complex:R-HSA-72593] mRNA:eIF4F:eIF4B:eIF4H [cytosol] - Homo sapiens [Complex:R-HSA-156804] 43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-165777] Phosphorylation and activation of eIF4B by activated S6K1 - Homo sapiens [BlackBoxEvent:R-HSA-72647] Cap-bound mRNA is activated by helicases - Homo sapiens
dbId	72589
displayName	EIF4B [cytosol]
endCoordinate	611
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-9817678] Eif4b [cytosol] - Mus musculus [GenomeEncodedEntity:R-RNO-72589] Ghost homologue of EIF4B [cytosol] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-72589] EIF4B [cytosol] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-72589] EIF4B [cytosol] - Bos taurus [EntityWithAccessionedSequence:R-SSC-72589] EIF4B [cytosol] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-72589] eif4ba [cytosol] - Danio rerio [EntityWithAccessionedSequence:R-XTR-72589] eif4b [cytosol] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-72589] EIF4B [cytosol] - Gallus gallus [GenomeEncodedEntity:R-DME-72589] Ghost homologue of EIF4B [cytosol] - Drosophila melanogaster [GenomeEncodedEntity:R-CEL-72589] Ghost homologue of EIF4B [cytosol] - Caenorhabditis elegans [GenomeEncodedEntity:R-DDI-72589] Ghost homologue of EIF4B [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-SPO-72589] sce3 [cytosol] - Schizosaccharomyces pombe [EntityWithAccessionedSequence:R-SCE-72589] TIF3 [cytosol] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-72589-2] NOP13 [cytosol] - Saccharomyces cerevisiae [DefinedSet:R-SCE-72589-3] Homologues of EIF4B [cytosol] - Saccharomyces cerevisiae [GenomeEncodedEntity:R-PFA-72589] Ghost homologue of EIF4B [cytosol] - Plasmodium falciparum
maxDepth	1
modified	[InstanceEdit:4084601] Orlic-Milacic, M, 2013-07-29
name	EIF4B eIF4B eIF-4B eukaryotic translation initiation factor 4B Eukaryotic translation initiation factor 4B
producedByEvent	[Reaction:R-HSA-429992] PARN deadenylates mRNA - Homo sapiens [Reaction:R-HSA-429955] CCR4-NOT complex deadenylates mRNA - Homo sapiens [Reaction:R-HSA-72619] eIF2:GTP is hydrolyzed, eIFs are released - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:P23588] UniProt:P23588 EIF4B
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-72589
startCoordinate	1
updateTrackers	[UpdateTracker:9888554] Update Tracker - [EntityWithAccessionedSequence:72589] EIF4B [cytosol] - v46:[modifyEndCoordinate, modifyName, modifyStartCoordinate] [UpdateTracker:9885350] Update Tracker - [EntityWithAccessionedSequence:72589] EIF4B [cytosol] - v45:[addName] [UpdateTracker:9867797] Update Tracker - [EntityWithAccessionedSequence:72589] EIF4B [cytosol] - v26:[modifyEndCoordinate, modifyStartCoordinate]

Referrals

(updatedInstance)	[UpdateTracker:9888554] Update Tracker - [EntityWithAccessionedSequence:72589] EIF4B [cytosol] - v46:[modifyEndCoordinate, modifyName, modifyStartCoordinate] [UpdateTracker:9885350] Update Tracker - [EntityWithAccessionedSequence:72589] EIF4B [cytosol] - v45:[addName] [UpdateTracker:9867797] Update Tracker - [EntityWithAccessionedSequence:72589] EIF4B [cytosol] - v26:[modifyEndCoordinate, modifyStartCoordinate]
(hasComponent)	[Complex:R-HSA-9822333] deadenylated mRNP regulated by BTG4 [cytosol] [Complex:R-HSA-9817647] mRNP regulated by BTG4 [cytosol] [Complex:R-HSA-8960059] Uridylated partially Deadenylated mRNA Complex [cytosol] [Complex:R-HSA-429977] Translatable mRNA Complex [cytosol] [Complex:R-HSA-429989] Partially Deadenylated mRNA Complex [cytosol] [Complex:R-HSA-156804] 43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] [Complex:R-HSA-156809] Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H [cytosol] [Complex:R-HSA-72593] mRNA:eIF4F:eIF4B:eIF4H [cytosol] [Complex:R-HSA-72592] 43S:mRNA:eIF4F:eIF4B:eIF4H [cytosol] [Complex:R-HSA-72594] 48S complex [cytosol]
(output)	[Reaction:R-HSA-429992] PARN deadenylates mRNA [Reaction:R-HSA-429955] CCR4-NOT complex deadenylates mRNA [Reaction:R-HSA-72619] eIF2:GTP is hydrolyzed, eIFs are released
(input)	[Reaction:R-HSA-165777] Phosphorylation and activation of eIF4B by activated S6K1 [BlackBoxEvent:R-HSA-72647] Cap-bound mRNA is activated by helicases

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