SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly

catalystActivity
catalystActivityReference [CatalystActivityReference:9643735] aldehyde-lyase activity of SHMT1 tetramer [cytosol] Affinity purification and characterization of serine hydroxymethyltransferases from rat liver
category transition
compartment
crossReference
dbId 71249
displayName SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly
eventOf
followingEvent
input
isInDisease false
isInferred false
literatureReference
maxDepth 1
modified [InstanceEdit:11080360] Weiser, Joel, 2026-03-16
name
  • SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly
  • (3S)-3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine => 4-(trimethylamino)butanal + glycine
  • beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine
orthologousEvent
output
precedingEvent
releaseDate 2004-07-06
reviewStatus [ReviewStatus:9821382] five stars
revised
schemaClass Reaction
species
stId R-HSA-71249
summation
updateTrackers
Cite Us!