Reactome | DNA2 [nucleoplasm]

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DNA2 [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-174442] Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer:DNA2 [nucleoplasm] - Homo sapiens [Complex:R-HSA-68466] Processive complex:Okazaki fragment:Flap:RPA heterotrimer:dna2 [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-69142] Recruitment of Dna2 endonuclease - Homo sapiens [Reaction:R-HSA-174451] Recruitment of DNA2 endonuclease to the C strand - Homo sapiens
dbId	68465
displayName	DNA2 [nucleoplasm]
endCoordinate	1060
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-68465] DNA2 [nucleoplasm] - Mus musculus [EntityWithAccessionedSequence:R-RNO-68465] DNA2 [nucleoplasm] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-68465] DNA2 [nucleoplasm] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-68465] DNA2 [nucleoplasm] - Bos taurus [EntityWithAccessionedSequence:R-SSC-68465] DNA2 [nucleoplasm] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-68465] dna2 [nucleoplasm] - Danio rerio [GenomeEncodedEntity:R-XTR-68465] Ghost homologue of DNA2 [nucleoplasm] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-68465] DNA2 [nucleoplasm] - Gallus gallus [EntityWithAccessionedSequence:R-DME-68465] Dna2 [nucleoplasm] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-68465] dna-2 [nucleoplasm] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-DDI-68465] DNA2 [nucleoplasm] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-SPO-68465] DNA2 [nucleoplasm] - Schizosaccharomyces pombe
maxDepth	1
modified	[InstanceEdit:73680] Gillespie, ME, 0000-00-00 00:00:00
name	DNA2 dna2 endonuclease DNA2-like homolog DNA replication helicase-like homolog
producedByEvent	[Reaction:R-HSA-69144] Removal of RNA primer and dissociation of RPA and Dna2 - Homo sapiens [Reaction:R-HSA-174441] Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:P51530] UniProt:P51530 DNA2
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-68465
startCoordinate	1
updateTrackers	[UpdateTracker:9879620] Update Tracker - [EntityWithAccessionedSequence:68465] DNA2 [nucleoplasm] - v44:[modifyEndCoordinate] [UpdateTracker:9884332] Update Tracker - [EntityWithAccessionedSequence:68465] DNA2 [nucleoplasm] - v45:[addName]

Referrals

(updatedInstance)	[UpdateTracker:9879620] Update Tracker - [EntityWithAccessionedSequence:68465] DNA2 [nucleoplasm] - v44:[modifyEndCoordinate] [UpdateTracker:9884332] Update Tracker - [EntityWithAccessionedSequence:68465] DNA2 [nucleoplasm] - v45:[addName]
(input)	[Reaction:R-HSA-69142] Recruitment of Dna2 endonuclease [Reaction:R-HSA-174451] Recruitment of DNA2 endonuclease to the C strand
(output)	[Reaction:R-HSA-69144] Removal of RNA primer and dissociation of RPA and Dna2 [Reaction:R-HSA-174441] Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand
(hasComponent)	[Complex:R-HSA-68466] Processive complex:Okazaki fragment:Flap:RPA heterotrimer:dna2 [nucleoplasm] [Complex:R-HSA-174442] Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer:DNA2 [nucleoplasm] [Complex:R-HSA-5685969] DNA2:WRN [nucleoplasm] [Complex:R-HSA-5685974] DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm]
(activeUnit)	[CatalystActivity:9669008] 5'-flap endonuclease activity of Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer:DNA2 [nucleoplasm]

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