Reactome | GBF1 [cytosol]

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GBF1 [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-9947741] NS5:GBF1 [cytosol] - Homo sapiens [Complex:R-HSA-6807800] RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-6811415] RAB:GTP recruits GBF1 to the Golgi membrane - Homo sapiens [Reaction:R-HSA-6807864] RAB1:GTP recruits GBF1 to the ERGIC - Homo sapiens
created	[InstanceEdit:6807750] Rothfels, Karen, 2015-11-03
dbId	6807751
displayName	GBF1 [cytosol]
endCoordinate	1860
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-6807751] Gbf1 [cytosol] - Mus musculus [EntityWithAccessionedSequence:R-RNO-6807751] Gbf1 [cytosol] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-6807751] GBF1 [cytosol] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-6807751] GBF1 [cytosol] - Bos taurus [EntityWithAccessionedSequence:R-SSC-6807751] GBF1 [cytosol] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-6807751] gbf1 [cytosol] - Danio rerio [GenomeEncodedEntity:R-XTR-6807751] Ghost homologue of GBF1 [cytosol] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-6807751] GBF1 [cytosol] - Gallus gallus [EntityWithAccessionedSequence:R-DME-6807751] garz [cytosol] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-6807751] gbf-1 [cytosol] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-DDI-6807751] GBF1 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-SPO-6807751] GBF1 [cytosol] - Schizosaccharomyces pombe [EntityWithAccessionedSequence:R-SCE-6807751] GEA2 [cytosol] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-PFA-6807751] GBF1 [cytosol] - Plasmodium falciparum
maxDepth	1
modified	[InstanceEdit:9967565] D'Eustachio, Peter, 2025-10-03
name	GBF1
producedByEvent	[Reaction:R-HSA-6811418] ARFGAPs stimulate ARF GTPase activity at the Golgi membrane - Homo sapiens [Reaction:R-HSA-6807877] ARFGAPs stimulate ARF GTPase activity - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:Q92538] UniProt:Q92538 GBF1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-6807751
startCoordinate	1
updateTrackers	[UpdateTracker:9972515] Update Tracker - [EntityWithAccessionedSequence:6807751] GBF1 [cytosol] - v95:[modifyEndCoordinate]

Referrals

(updatedInstance)	[UpdateTracker:9972515] Update Tracker - [EntityWithAccessionedSequence:6807751] GBF1 [cytosol] - v95:[modifyEndCoordinate]
(output)	[Reaction:R-HSA-6811418] ARFGAPs stimulate ARF GTPase activity at the Golgi membrane [Reaction:R-HSA-6807877] ARFGAPs stimulate ARF GTPase activity
(input)	[Reaction:R-HSA-6811415] RAB:GTP recruits GBF1 to the Golgi membrane [Reaction:R-HSA-6807864] RAB1:GTP recruits GBF1 to the ERGIC
(hasComponent)	[Complex:R-HSA-9947741] NS5:GBF1 [cytosol] [Complex:R-HSA-6807800] RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(activeUnit)	[CatalystActivity:6807858] guanyl-nucleotide exchange factor activity of RAB1:GTP:GBF1:USO1:ARF:GDP [endoplasmic reticulum-Golgi intermediate compartment membrane]

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