Reactome | RAB:GTP recruits GBF1 to the Golgi membrane

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RAB:GTP recruits GBF1 to the Golgi membrane Show undefined attributes

authored	[InstanceEdit:6809025] Rothfels, Karen, 2015-11-09
category	binding
compartment	[Compartment:20699] Golgi membrane
created	[InstanceEdit:6811413] Rothfels, Karen, 2015-11-19
dbId	6811415
displayName	RAB:GTP recruits GBF1 to the Golgi membrane
edited	[InstanceEdit:6809025] Rothfels, Karen, 2015-11-09
eventOf	[Pathway:R-HSA-6811434] COPI-dependent Golgi-to-ER retrograde traffic - Homo sapiens
followingEvent	[Reaction:R-HSA-6811411] GBF1 recruits ARF:GDP to the Golgi - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-6807751] GBF1 [cytosol] [Complex:R-HSA-6808823] RAB1:GTP [Golgi membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:6804924] Rab1b interacts with GBF1 and modulates both ARF1 dynamics and COPI association [LiteratureReference:6805368] GBF1, a guanine nucleotide exchange factor for ADP-ribosylation factors, is localized to the cis-Golgi and involved in membrane association of the COPI coat [LiteratureReference:6805348] Dissection of membrane dynamics of the ARF-guanine nucleotide exchange factor GBF1 [LiteratureReference:5623301] Dissecting the role of the ARF guanine nucleotide exchange factor GBF1 in Golgi biogenesis and protein trafficking [LiteratureReference:6805364] GBF1, a cis-Golgi and VTCs-localized ARF-GEF, is implicated in ER-to-Golgi protein traffic [LiteratureReference:5688472] COPII and COPI traffic at the ER-Golgi interface [LiteratureReference:6804916] Isoform-selective effects of the depletion of ADP-ribosylation factors 1-5 on membrane traffic [LiteratureReference:6804905] Characterization of class I and II ADP-ribosylation factors (Arfs) in live cells: GDP-bound class II Arfs associate with the ER-Golgi intermediate compartment independently of GBF1 [LiteratureReference:6804887] ARF proteins: roles in membrane traffic and beyond
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	RAB:GTP recruits GBF1 to the Golgi membrane
orthologousEvent	[Reaction:R-PFA-6811415] RAB:GTP recruits GBF1 to the Golgi membrane - Plasmodium falciparum [Reaction:R-SCE-6811415] RAB:GTP recruits GBF1 to the Golgi membrane - Saccharomyces cerevisiae [Reaction:R-SPO-6811415] RAB:GTP recruits GBF1 to the Golgi membrane - Schizosaccharomyces pombe [Reaction:R-DDI-6811415] RAB:GTP recruits GBF1 to the Golgi membrane - Dictyostelium discoideum [Reaction:R-CEL-6811415] RAB:GTP recruits GBF1 to the Golgi membrane - Caenorhabditis elegans [Reaction:R-DME-6811415] RAB:GTP recruits GBF1 to the Golgi membrane - Drosophila melanogaster [Reaction:R-DRE-6811415] RAB:GTP recruits GBF1 to the Golgi membrane - Danio rerio [Reaction:R-BTA-6811415] RAB:GTP recruits GBF1 to the Golgi membrane - Bos taurus [Reaction:R-CFA-6811415] RAB:GTP recruits GBF1 to the Golgi membrane - Canis familiaris [Reaction:R-RNO-6811415] RAB:GTP recruits GBF1 to the Golgi membrane - Rattus norvegicus [Reaction:R-MMU-6811415] RAB:GTP recruits GBF1 to the Golgi membrane - Mus musculus
output	[Complex:R-HSA-6811366] RAB1:GTP:GBF1 [Golgi membrane]
releaseDate	2016-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8855182] Gillespie, Marc E, 2016-02-02
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-6811415
summation	[Summation:6811285] In its GTP-bound active state, RAB1 recruits the ARF GEF GBF...

Referrals

(precedingEvent)	[Reaction:R-HSA-6811411] GBF1 recruits ARF:GDP to the Golgi
(hasEvent)	[Pathway:R-HSA-6811434] COPI-dependent Golgi-to-ER retrograde traffic

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