Reactome | APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX

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APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX Show undefined attributes

authored	[InstanceEdit:6806965] Jassal, Bijay, 2015-10-28
catalystActivity	[CatalystActivity:6807480] NAD(P)HX epimerase activity of APOA1BP dimer [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:6806965] Jassal, Bijay, 2015-10-28
crossReference	[DatabaseIdentifier:12668001] RHEA:32216 [DatabaseIdentifier:9938241] RHEA:32216
dbId	6806966
displayName	APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX
edited	[InstanceEdit:6806965] Jassal, Bijay, 2015-10-28
eventOf	[Pathway:R-HSA-196807] Nicotinate metabolism - Homo sapiens
followingEvent	[Reaction:R-HSA-6806967] CARKD dehydrates S-NAD(P)HX to NADPH - Homo sapiens
input	[SimpleEntity:R-ALL-6807473] R-NADPHX [mitochondrial matrix]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:6807472] Cloning and characterization of a novel apolipoprotein A-I binding protein, AI-BP, secreted by cells of the kidney proximal tubules in response to HDL or ApoA-I [LiteratureReference:6807488] Extremely conserved ATP- or ADP-dependent enzymatic system for nicotinamide nucleotide repair
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX (6R)-NADHX => (6S)-NADHX
orthologousEvent	[Reaction:R-RNO-6806966] APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX - Rattus norvegicus [Reaction:R-PFA-6806966] APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX - Plasmodium falciparum [Reaction:R-SCE-6806966] APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX - Saccharomyces cerevisiae [Reaction:R-SPO-6806966] APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX - Schizosaccharomyces pombe [Reaction:R-DDI-6806966] APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX - Dictyostelium discoideum [Reaction:R-CEL-6806966] APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX - Caenorhabditis elegans [Reaction:R-DME-6806966] APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX - Drosophila melanogaster [Reaction:R-GGA-6806966] APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX - Gallus gallus [Reaction:R-DRE-6806966] APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX - Danio rerio [Reaction:R-SSC-6806966] APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX - Sus scrofa [Reaction:R-BTA-6806966] APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX - Bos taurus [Reaction:R-CFA-6806966] APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX - Canis familiaris [Reaction:R-MMU-6806966] APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX - Mus musculus
output	[SimpleEntity:R-ALL-6807477] S-NADPHX [mitochondrial matrix]
releaseDate	2016-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8851787] D'Eustachio, Peter, 2016-01-11
revised	[InstanceEdit:8940089] Jassal, Bijay, 2016-09-23
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-6806966
summation	[Summation:6807476] NAD(P)H-hydrate epimerase (APOA1BP) is a homodimeric protein...

Referrals

(hasEvent)	[Pathway:R-HSA-196807] Nicotinate metabolism
(precedingEvent)	[Reaction:R-HSA-6806967] CARKD dehydrates S-NAD(P)HX to NADPH