Reactome | CARKD dehydrates S-NAD(P)HX to NADPH

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CARKD dehydrates S-NAD(P)HX to NADPH Show undefined attributes

authored	[InstanceEdit:6806965] Jassal, Bijay, 2015-10-28
catalystActivity	[CatalystActivity:8847933] ATP-dependent NAD(P)H-hydrate dehydratase activity of CARKD [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:6806965] Jassal, Bijay, 2015-10-28
crossReference	[DatabaseIdentifier:11880207] Rhea:32232
dbId	6806967
displayName	CARKD dehydrates S-NAD(P)HX to NADPH
edited	[InstanceEdit:6806965] Jassal, Bijay, 2015-10-28
eventOf	[Pathway:R-HSA-197264] Nicotinamide salvaging - Homo sapiens
input	[SimpleEntity:R-ALL-113593] ATP [mitochondrial matrix] [SimpleEntity:R-ALL-6807477] S-NADPHX [mitochondrial matrix]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:6807488] Extremely conserved ATP- or ADP-dependent enzymatic system for nicotinamide nucleotide repair
modified	[InstanceEdit:11879863] Wright, Adam, 2024-03-11
name	CARKD dehydrates S-NAD(P)HX to NADPH
orthologousEvent	[Reaction:R-PFA-6806967] CARKD dehydrates S-NAD(P)HX to NADPH - Plasmodium falciparum [Reaction:R-SCE-6806967] CARKD dehydrates S-NAD(P)HX to NADPH - Saccharomyces cerevisiae [Reaction:R-SPO-6806967] CARKD dehydrates S-NAD(P)HX to NADPH - Schizosaccharomyces pombe [Reaction:R-DDI-6806967] CARKD dehydrates S-NAD(P)HX to NADPH - Dictyostelium discoideum [Reaction:R-CEL-6806967] CARKD dehydrates S-NAD(P)HX to NADPH - Caenorhabditis elegans [Reaction:R-DME-6806967] CARKD dehydrates S-NAD(P)HX to NADPH - Drosophila melanogaster [Reaction:R-GGA-6806967] CARKD dehydrates S-NAD(P)HX to NADPH - Gallus gallus [Reaction:R-XTR-6806967] CARKD dehydrates S-NAD(P)HX to NADPH - Xenopus tropicalis [Reaction:R-DRE-6806967] CARKD dehydrates S-NAD(P)HX to NADPH - Danio rerio [Reaction:R-SSC-6806967] CARKD dehydrates S-NAD(P)HX to NADPH - Sus scrofa [Reaction:R-BTA-6806967] CARKD dehydrates S-NAD(P)HX to NADPH - Bos taurus [Reaction:R-CFA-6806967] CARKD dehydrates S-NAD(P)HX to NADPH - Canis familiaris [Reaction:R-RNO-6806967] CARKD dehydrates S-NAD(P)HX to NADPH - Rattus norvegicus [Reaction:R-MMU-6806967] CARKD dehydrates S-NAD(P)HX to NADPH - Mus musculus
output	[SimpleEntity:R-ALL-113581] ADP [mitochondrial matrix] 3 × [SimpleEntity:R-ALL-113529] H+ [mitochondrial matrix] [SimpleEntity:R-ALL-113600] NADPH [mitochondrial matrix] [SimpleEntity:R-ALL-113548] Pi [mitochondrial matrix]
precedingEvent	[Reaction:R-HSA-6806966] APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX - Homo sapiens
releaseDate	2016-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8851787] D'Eustachio, Peter, 2016-01-11
revised	[InstanceEdit:8940089] Jassal, Bijay, 2016-09-23
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-6806967
summation	[Summation:6807489] Human ATP-dependent (S)-NAD(P)H-hydrate dehydratase (CARKD) ...

Referrals

(hasEvent)

[Pathway:R-HSA-197264] Nicotinamide salvaging