Reactome | p-S166,S188-MDM2:p-S346,S367,S403-MDM4 [nucleoplasm]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:9952147] ubiquitin protein ligase activity of p-S166,S188-MDM2:p-S346,S367,S403-MDM4 [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[Reaction:R-MMU-6804724] MDM2 ubiquitinates phosphorylated MDM4 - Mus musculus
created	[InstanceEdit:9864362] Wright, Adam, 2024-03-07
dbId	9887425
displayName	p-S166,S188-MDM2:p-S346,S367,S403-MDM4 [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-MMU-6793669] phospho-Mdm2 [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-349441] phospho-Mdm4 [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-6804936] p-S166,S188-MDM2:p-S346,S367,S403-MDM4 [nucleoplasm] - Homo sapiens
name	p-S166,S188-MDM2:p-S346,S367,S403-MDM4
producedByEvent	[Reaction:R-MMU-5689972] USP2 deubiquitinates MDM2,MDM4 - Mus musculus [Reaction:R-MMU-349426] Phosphorylation of MDM4 by CHEK2 - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-6804936
summation	[Summation:9864367] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[Reaction:R-MMU-5689972] USP2 deubiquitinates MDM2,MDM4 [Reaction:R-MMU-349426] Phosphorylation of MDM4 by CHEK2
(hasCandidate)	[CandidateSet:R-MMU-6805030] p-S166,S188-MDM2:(p-S166,S188-MDM2,p-S346,S367,S403-MDM4) [nucleoplasm]
(inferredTo)	[Complex:R-HSA-6804936] p-S166,S188-MDM2:p-S346,S367,S403-MDM4 [nucleoplasm]
(input)	[Reaction:R-MMU-6804724] MDM2 ubiquitinates phosphorylated MDM4
(physicalEntity)	[CatalystActivity:9952147] ubiquitin protein ligase activity of p-S166,S188-MDM2:p-S346,S367,S403-MDM4 [nucleoplasm]