Reactome | STEAP3 binds BNIP3L

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STEAP3 binds BNIP3L Show undefined attributes

authored	[InstanceEdit:6804719] Orlic-Milacic, Marija, 2015-10-14
category	binding
compartment	[Compartment:74700] endosome membrane [Compartment:17906] mitochondrial outer membrane
created	[InstanceEdit:6801197] Orlic-Milacic, Marija, 2015-09-30
dbId	6801195
displayName	STEAP3 binds BNIP3L
edited	[InstanceEdit:6804719] Orlic-Milacic, Marija, 2015-10-14
eventOf	[Pathway:R-HSA-6803204] TP53 Regulates Transcription of Genes Involved in Cytochrome C Release - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-6798001] BNIP3L [mitochondrial outer membrane] [EntityWithAccessionedSequence:R-HSA-917861] STEAP3 [endosome membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:6801169] The p53-inducible TSAP6 gene product regulates apoptosis and the cell cycle and interacts with Nix and the Myt1 kinase [LiteratureReference:6801199] Intramitochondrial recruitment of endolysosomes mediates Smac degradation and constitutes a novel intrinsic apoptosis antagonizing function of XIAP E3 ligase
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	STEAP3 binds BNIP3L
orthologousEvent	[Reaction:R-GGA-6801195] STEAP3 binds BNIP3L - Gallus gallus [Reaction:R-DRE-6801195] STEAP3 binds BNIP3L - Danio rerio [Reaction:R-SSC-6801195] STEAP3 binds BNIP3L - Sus scrofa [Reaction:R-BTA-6801195] STEAP3 binds BNIP3L - Bos taurus [Reaction:R-CFA-6801195] STEAP3 binds BNIP3L - Canis familiaris [Reaction:R-RNO-6801195] STEAP3 binds BNIP3L - Rattus norvegicus [Reaction:R-MMU-6801195] STEAP3 binds BNIP3L - Mus musculus
output	[Complex:R-HSA-6801198] STEAP3:BNIP3L [mitochondrial outer membrane]
precedingEvent	[BlackBoxEvent:R-HSA-6801184] TP53 stimulates STEAP3 expression - Homo sapiens [BlackBoxEvent:R-HSA-6798004] TP53 stimulates BNIP3L expression - Homo sapiens
releaseDate	2016-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8855677] Zaccara, Sara, 2016-02-04 [InstanceEdit:8855680] Inga, Alberto, 2016-02-04
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-6801195
summation	[Summation:6801196] STEAP3 (TSAP6) forms a complex with a pro-apoptotic protein ...

Referrals

(hasEvent)

[Pathway:R-HSA-6803204] TP53 Regulates Transcription of Genes Involved in Cytochrome C Release