Reactome | TP53 binds the AIFM2 gene promoter

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TP53 binds the AIFM2 gene promoter Show undefined attributes

authored	[InstanceEdit:6804719] Orlic-Milacic, Marija, 2015-10-14
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:6791297] Orlic-Milacic, Marija, 2015-08-20
dbId	6791302
displayName	TP53 binds the AIFM2 gene promoter
edited	[InstanceEdit:6804719] Orlic-Milacic, Marija, 2015-10-14
eventOf	[Pathway:R-HSA-6803204] TP53 Regulates Transcription of Genes Involved in Cytochrome C Release - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-6791306] TP53 stimulates AIFM2 gene expression - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-6791303] AIFM2 Gene [nucleoplasm] [Complex:R-HSA-3222171] p-S15,S20-TP53 Tetramer [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:6791300] AMID is a p53-inducible gene downregulated in tumors
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	TP53 binds the AIFM2 gene promoter
output	[Complex:R-HSA-6791298] p-S15,S20-TP53 Tetramer:AIFM2 Gene [nucleoplasm]
precedingEvent	[Reaction:R-HSA-6799246] CHEK1 phosphorylates TP53 - Homo sapiens [Reaction:R-HSA-69685] CHEK2 phosphorylates TP53 - Homo sapiens [Reaction:R-HSA-6805285] PLK3 phosphorylates TP53 - Homo sapiens
releaseDate	2016-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8855677] Zaccara, Sara, 2016-02-04 [InstanceEdit:8855680] Inga, Alberto, 2016-02-04
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-6791302
summation	[Summation:6791307] TP53 (p53) binds the promoter of the AIFM2 (AMID) gene, whic...

Referrals

(precedingEvent)	[BlackBoxEvent:R-HSA-6791306] TP53 stimulates AIFM2 gene expression
(hasEvent)	[Pathway:R-HSA-6803204] TP53 Regulates Transcription of Genes Involved in Cytochrome C Release

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