Reactome | IL10RB:TYK2 [plasma membrane]

Schema > Complex > Entries

IL10RB:TYK2 [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-8987146] IFNL2,IFNL3:IFNLR1:JAK1:IL10RB:TYK2 [plasma membrane] - Homo sapiens [Complex:R-HSA-448637] IFNL1:IFNLR1:JAK1:IL10RB:TYK2 [plasma membrane] - Homo sapiens
consumedByEvent	[BlackBoxEvent:R-HSA-8987105] IFNL2,IFNL3 bind IL10RB:TYK2 and IFNLR1:JAK1 - Homo sapiens [Reaction:R-HSA-8854645] IL22:IL22RA1:JAK1 binds IL10RB:TYK2 - Homo sapiens [Reaction:R-HSA-449811] IL10 dimer:2xIL10RA1:JAK1 binds IL10RB:TYK2 - Homo sapiens [Reaction:R-HSA-449811] IL10 dimer:2xIL10RA1:JAK1 binds IL10RB:TYK2 - Homo sapiens [Reaction:R-HSA-8986480] IL26:IL20RA:JAK1 binds IL10RB:TYK2 - Homo sapiens [Reaction:R-HSA-448661] IFNL1 binds IL10RB:TYK2 and IFNLR1:JAK1 - Homo sapiens
created	[InstanceEdit:6784364] Jupe, Steve, 2015-06-19
dbId	6784360
displayName	IL10RB:TYK2 [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-HSA-448423] IL10RB [plasma membrane] [EntityWithAccessionedSequence:R-HSA-877348] TYK2 [cytosol]
inDisease	false
includedLocation	[Compartment:70101] cytosol
inferredTo	[Complex:R-MMU-6784360] IL10RB:TYK2 [plasma membrane] - Mus musculus [Complex:R-RNO-6784360] IL10RB:TYK2 [plasma membrane] - Rattus norvegicus [Complex:R-CFA-6784360] IL10RB:TYK2 [plasma membrane] - Canis familiaris [Complex:R-BTA-6784360] IL10RB:TYK2 [plasma membrane] - Bos taurus [Complex:R-SSC-6784360] IL10RB:TYK2 [plasma membrane] - Sus scrofa [Complex:R-DRE-6784360] IL10RB:TYK2 [plasma membrane] - Danio rerio [Complex:R-XTR-6784360] IL10RB:TYK2 [plasma membrane] - Xenopus tropicalis [Complex:R-GGA-6784360] IL10RB:TYK2 [plasma membrane] - Gallus gallus
isChimeric	false
literatureReference	[LiteratureReference:8987085] The molecular basis of IL-10 function: from receptor structure to the onset of signaling
maxDepth	2
modified	[InstanceEdit:8987421] Duenas, Corina, 2017-05-05
name	IL10RB:TYK2
producedByEvent	[Reaction:R-HSA-8987223] IL10RB binds TYK2 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-6784360
updateTrackers	[UpdateTracker:9897058] Update Tracker - [Complex:6784360] IL10RB:TYK2 [plasma membrane] - v61:[addLiteratureReference]

Referrals

(updatedInstance)	[UpdateTracker:9897058] Update Tracker - [Complex:6784360] IL10RB:TYK2 [plasma membrane] - v61:[addLiteratureReference]
(hasComponent)	[Complex:R-HSA-8987146] IFNL2,IFNL3:IFNLR1:JAK1:IL10RB:TYK2 [plasma membrane] [Complex:R-HSA-8854697] IL22:IL22RA1:JAK1:IL10RB:TYK2 [plasma membrane] [Complex:R-HSA-449832] IL10 dimer:2xIL10RA:JAK1:2xIL10RB:TYK2 [plasma membrane] [Complex:R-HSA-8986478] IL26:IL20RA:JAK1:IL10RB:TYK2 [plasma membrane] [Complex:R-HSA-448637] IFNL1:IFNLR1:JAK1:IL10RB:TYK2 [plasma membrane]
(input)	[BlackBoxEvent:R-HSA-8987105] IFNL2,IFNL3 bind IL10RB:TYK2 and IFNLR1:JAK1 [Reaction:R-HSA-8854645] IL22:IL22RA1:JAK1 binds IL10RB:TYK2 [Reaction:R-HSA-449811] IL10 dimer:2xIL10RA1:JAK1 binds IL10RB:TYK2 [Reaction:R-HSA-8986480] IL26:IL20RA:JAK1 binds IL10RB:TYK2 [Reaction:R-HSA-448661] IFNL1 binds IL10RB:TYK2 and IFNLR1:JAK1
(output)	[Reaction:R-HSA-8987223] IL10RB binds TYK2

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