Reactome | Gap-filling DNA repair synthesis and ligation in TC-NER

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Gap-filling DNA repair synthesis and ligation in TC-NER Show undefined attributes

authored	[InstanceEdit:110275] Hoeijmakers, JH, 2004-01-29 18:08:33 [InstanceEdit:6783704] Orlic-Milacic, Marija, 2015-06-16
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:6782207] Orlic-Milacic, Marija, 2015-06-05
crossReference	[DatabaseIdentifier:12819455] BioModels Database:BIOMD0000000293 [DatabaseIdentifier:12819457] BioModels Database:BIOMD0000000220
dbId	6782210
deleted	[Deleted:6793357] Deletion of instance: 109977 [Deleted:6793371] Deletion of instance: 109979
displayName	Gap-filling DNA repair synthesis and ligation in TC-NER
edited	[InstanceEdit:6783704] Orlic-Milacic, Marija, 2015-06-16 [InstanceEdit:9862096] Orlic-Milacic, Marija, 2024-02-22
eventOf	[Pathway:R-HSA-6781827] Transcription-Coupled Nucleotide Excision Repair (TC-NER) - Homo sapiens
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-6782208] Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER - Homo sapiens [Reaction:R-HSA-6782227] Ligation of newly synthesized repair patch to incised DNA in TC-NER - Homo sapiens
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5690036] Coordination of dual incision and repair synthesis in human nucleotide excision repair [LiteratureReference:5690489] Three DNA polymerases, recruited by different mechanisms, carry out NER repair synthesis in human cells [LiteratureReference:9861997] DNA Ligases I and III Support Nucleotide Excision Repair in DT40 Cells with Similar Efficiency [LiteratureReference:9861999] Functional redundancy between DNA ligases I and III in DNA replication in vertebrate cells
maxDepth	2
modified	[InstanceEdit:12819426] Weiser, Joel, 2026-02-23
name	Gap-filling DNA repair synthesis and ligation in TC-NER
orthologousEvent	[Pathway:R-MMU-6782210] Gap-filling DNA repair synthesis and ligation in TC-NER - Mus musculus [Pathway:R-PFA-6782210] Gap-filling DNA repair synthesis and ligation in TC-NER - Plasmodium falciparum [Pathway:R-SCE-6782210] Gap-filling DNA repair synthesis and ligation in TC-NER - Saccharomyces cerevisiae [Pathway:R-SPO-6782210] Gap-filling DNA repair synthesis and ligation in TC-NER - Schizosaccharomyces pombe [Pathway:R-DDI-6782210] Gap-filling DNA repair synthesis and ligation in TC-NER - Dictyostelium discoideum [Pathway:R-CEL-6782210] Gap-filling DNA repair synthesis and ligation in TC-NER - Caenorhabditis elegans [Pathway:R-DME-6782210] Gap-filling DNA repair synthesis and ligation in TC-NER - Drosophila melanogaster [Pathway:R-GGA-6782210] Gap-filling DNA repair synthesis and ligation in TC-NER - Gallus gallus [Pathway:R-XTR-6782210] Gap-filling DNA repair synthesis and ligation in TC-NER - Xenopus tropicalis [Pathway:R-DRE-6782210] Gap-filling DNA repair synthesis and ligation in TC-NER - Danio rerio [Pathway:R-SSC-6782210] Gap-filling DNA repair synthesis and ligation in TC-NER - Sus scrofa [Pathway:R-BTA-6782210] Gap-filling DNA repair synthesis and ligation in TC-NER - Bos taurus [Pathway:R-CFA-6782210] Gap-filling DNA repair synthesis and ligation in TC-NER - Canis familiaris [Pathway:R-RNO-6782210] Gap-filling DNA repair synthesis and ligation in TC-NER - Rattus norvegicus
precedingEvent	[Pathway:R-HSA-6782135] Dual incision in TC-NER - Homo sapiens
releaseDate	2004-03-06
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:6790576] Fousteri, Maria, 2015-08-03
revised	[InstanceEdit:6783704] Orlic-Milacic, Marija, 2015-06-16
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-6782210
summation	[Summation:6782940] In transcription-coupled nucleotide excision repair (TC-NER)...
updateTrackers	[UpdateTracker:9864353] Update Tracker - [Pathway:6782210] Gap-filling DNA repair synthesis and ligation in TC-NER - v88:[add_removeLiteratureReference, modifyText, updateContainedRLE]

Referrals

(updatedInstance)	[UpdateTracker:9864353] Update Tracker - [Pathway:6782210] Gap-filling DNA repair synthesis and ligation in TC-NER - v88:[add_removeLiteratureReference, modifyText, updateContainedRLE]
(replacementInstances)	[Deleted:6793357] Deletion of instance: 109977 [Deleted:6793371] Deletion of instance: 109979
(hasEvent)	[Pathway:R-HSA-6781827] Transcription-Coupled Nucleotide Excision Repair (TC-NER)

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