Reactome | MAP2K1 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

MAP2K1 [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-5672683] MAP2K1 dimer [cytosol] - Homo sapiens [Complex:R-HSA-5672683] MAP2K1 dimer [cytosol] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-5211340] Anthrax lef cleaves target cell MAP2K1 (MEK1) - Homo sapiens
dbId	59502
displayName	MAP2K1 [cytosol]
endCoordinate	393
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-59502] MAP2K1 [cytosol] - Mus musculus [EntityWithAccessionedSequence:R-RNO-59502] MAP2K1 [cytosol] - Rattus norvegicus [EntityWithAccessionedSequence:R-BTA-59502] MAP2K1 [cytosol] - Bos taurus [EntityWithAccessionedSequence:R-DRE-59502] MAP2K1 [cytosol] - Danio rerio [EntityWithAccessionedSequence:R-DME-59502] MAP2K1 [cytosol] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-59502] MAP2K1 [cytosol] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-DDI-59502] MAP2K1 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-SPO-59502] MAP2K1 [cytosol] - Schizosaccharomyces pombe [EntityWithAccessionedSequence:R-SPO-59502-2] MAP2K1 [cytosol] - Schizosaccharomyces pombe [EntityWithAccessionedSequence:R-SPO-59502-3] MAP2K1 [cytosol] - Schizosaccharomyces pombe [DefinedSet:R-SPO-59502-4] Homologues of MAP2K1 [cytosol] - Schizosaccharomyces pombe [EntityWithAccessionedSequence:R-SCE-59502] MAP2K1 [cytosol] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-59502-2] MAP2K1 [cytosol] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-59502-3] MAP2K1 [cytosol] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-59502-4] MAP2K1 [cytosol] - Saccharomyces cerevisiae [DefinedSet:R-SCE-59502-5] Homologues of MAP2K1 [cytosol] - Saccharomyces cerevisiae
maxDepth	1
memberOf	[DefinedSet:R-HSA-112336] MAP2K1 [cytosol] - Homo sapiens
modified	[InstanceEdit:9938686] D'Eustachio, Peter, 2025-02-18
name	MAP2K1 MEK1 Dual specificity mitogen-activated protein kinase kinase 1 (EC 2.7.1.-) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Dual specificity mitogen-activated protein kinase kinase 1 MAP kinase kinase 1 MAPKK 1 ERK activator kinase 1 MAPK/ERK kinase 1
referenceEntity	[ReferenceGeneProduct:uniprot:Q02750] UniProt:Q02750 MAP2K1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-59502
startCoordinate	1
updateTrackers	[UpdateTracker:9878943] Update Tracker - [EntityWithAccessionedSequence:59502] MAP2K1 [cytosol] - v44:[modifyEndCoordinate, modifyStartCoordinate] [UpdateTracker:9882604] Update Tracker - [EntityWithAccessionedSequence:59502] MAP2K1 [cytosol] - v45:[addName] [UpdateTracker:9939851] Update Tracker - [EntityWithAccessionedSequence:59502] MAP2K1 [cytosol] - v92:[modifyStartCoordinate]

Referrals

(updatedInstance)	[UpdateTracker:9878943] Update Tracker - [EntityWithAccessionedSequence:59502] MAP2K1 [cytosol] - v44:[modifyEndCoordinate, modifyStartCoordinate] [UpdateTracker:9882604] Update Tracker - [EntityWithAccessionedSequence:59502] MAP2K1 [cytosol] - v45:[addName] [UpdateTracker:9939851] Update Tracker - [EntityWithAccessionedSequence:59502] MAP2K1 [cytosol] - v92:[modifyStartCoordinate]
(input)	[Reaction:R-HSA-5211340] Anthrax lef cleaves target cell MAP2K1 (MEK1)
(hasMember)	[DefinedSet:R-HSA-112336] MAP2K1 [cytosol] [DefinedSet:R-HSA-451647] MAP2K1,MAP2K4 [cytosol]
(hasComponent)	[Complex:R-HSA-5672683] MAP2K1 dimer [cytosol] [Complex:R-HSA-5672686] MAP2K1:MAPK2K2 heterodimer [cytosol]

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