Reactome | A4GNT transfers GlcNAc to core 2 mucins

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A4GNT transfers GlcNAc to core 2 mucins Show undefined attributes

authored	[InstanceEdit:5694479] Jassal, Bijay, 2015-05-21
catalystActivity	[CatalystActivity:5694504] acetylglucosaminyltransferase activity of A4GNT [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen
created	[InstanceEdit:5694479] Jassal, Bijay, 2015-05-21
dbId	5694487
displayName	A4GNT transfers GlcNAc to core 2 mucins
edited	[InstanceEdit:5694479] Jassal, Bijay, 2015-05-21
eventOf	[Pathway:R-HSA-913709] O-linked glycosylation of mucins - Homo sapiens
input	[DefinedSet:R-HSA-1462066] Core 2 mucins [Golgi lumen] [SimpleEntity:R-ALL-914003] UDP-GlcNAc [Golgi lumen]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5694469] Expression cloning of a human alpha1, 4-N-acetylglucosaminyltransferase that forms GlcNAcalpha1-->4Galbeta-->R, a glycan specifically expressed in the gastric gland mucous cell-type mucin [LiteratureReference:5694477] Immunohistochemical demonstration of alpha1,4-N-acetylglucosaminyltransferase that forms GlcNAcalpha1,4Galbeta residues in human gastrointestinal mucosa
maxDepth	1
modified	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
name	A4GNT transfers GlcNAc to core 2 mucins
orthologousEvent	[Reaction:R-DME-5694487] A4GNT transfers GlcNAc to core 2 mucins - Drosophila melanogaster [Reaction:R-GGA-5694487] A4GNT transfers GlcNAc to core 2 mucins - Gallus gallus [Reaction:R-XTR-5694487] A4GNT transfers GlcNAc to core 2 mucins - Xenopus tropicalis [Reaction:R-SSC-5694487] A4GNT transfers GlcNAc to core 2 mucins - Sus scrofa [Reaction:R-BTA-5694487] A4GNT transfers GlcNAc to core 2 mucins - Bos taurus [Reaction:R-CFA-5694487] A4GNT transfers GlcNAc to core 2 mucins - Canis familiaris [Reaction:R-RNO-5694487] A4GNT transfers GlcNAc to core 2 mucins - Rattus norvegicus [Reaction:R-MMU-5694487] A4GNT transfers GlcNAc to core 2 mucins - Mus musculus
output	[DefinedSet:R-HSA-6784268] Core 2a mucins [Golgi lumen] [SimpleEntity:R-ALL-205687] UDP [Golgi lumen]
precedingEvent	[Reaction:R-HSA-914012] GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins - Homo sapiens
releaseDate	2015-09-22
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:6785241] D'Eustachio, Peter, 2015-06-26
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-5694487
summation	[Summation:5694450] Alpha-1,4-N-acetylglucosaminyltransferase (A4GNT) can cataly...

Referrals

(hasEvent)

[Pathway:R-HSA-913709] O-linked glycosylation of mucins