Reactome | Diseases of signal transduction by growth factor receptors and second messengers

Schema > Pathway > Entries

Diseases of signal transduction by growth factor receptors and second messengers Show undefined attributes

created	[InstanceEdit:5663200] D'Eustachio, Peter, 2015-01-15
crossReference	[DatabaseIdentifier:12020795] Mondo:0000001
dbId	5663202
disease	[Disease:5662932] disease
displayName	Diseases of signal transduction by growth factor receptors and second messengers
eventOf	[TopLevelPathway:R-HSA-1643685] Disease - Homo sapiens
figure	[Figure:9698289] /figures/ehld/R-HSA-5663202.svg
hasDiagram	true
hasEHLD	true
hasEvent	[Pathway:R-HSA-1643713] Signaling by EGFR in Cancer - Homo sapiens [Pathway:R-HSA-1226099] Signaling by FGFR in disease - Homo sapiens [Pathway:R-HSA-1227990] Signaling by ERBB2 in Cancer - Homo sapiens [Pathway:R-HSA-2219528] PI3K/AKT Signaling in Cancer - Homo sapiens [Pathway:R-HSA-2644603] Signaling by NOTCH1 in Cancer - Homo sapiens [Pathway:R-HSA-3304351] Signaling by TGF-beta Receptor Complex in Cancer - Homo sapiens [Pathway:R-HSA-4791275] Signaling by WNT in cancer - Homo sapiens [Pathway:R-HSA-5387390] Hh mutants abrogate ligand secretion - Homo sapiens [Pathway:R-HSA-6802957] Oncogenic MAPK signaling - Homo sapiens [Pathway:R-HSA-9669938] Signaling by KIT in disease - Homo sapiens [Pathway:R-HSA-9671555] Signaling by PDGFR in disease - Homo sapiens [Pathway:R-HSA-9682385] FLT3 signaling in disease - Homo sapiens [Pathway:R-HSA-9700206] Signaling by ALK in cancer - Homo sapiens [Pathway:R-HSA-9842640] Signaling by LTK in cancer - Homo sapiens
isInDisease	true
isInferred	false
lastUpdatedDate	2023-06-07
literatureReference	[LiteratureReference:5663203] The evolution of signalling pathways in animal development
maxDepth	6
modified	[InstanceEdit:9863571] Rothfels, Karen, 2024-03-04
name	Diseases of signal transduction by growth factor receptors and second messengers
previousReviewStatus	[ReviewStatus:9821384] two stars
releaseDate	2014-12-11
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9855942] D'Eustachio, Peter, 2023-12-08
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-5663202
summation	[Summation:5663198] Signaling processes are central to human physiology (e.g., P...
updateTrackers	[UpdateTracker:9777590] Update Tracker - [Pathway:5663202] Diseases of signal transduction by growth factor receptors and second messengers - v70:[updateContainedPathway] [UpdateTracker:9853268] Update Tracker - [Pathway:5663202] Diseases of signal transduction by growth factor receptors and second messengers - v87:[updateContainedPathway] [UpdateTracker:9835723] Update Tracker - [Pathway:5663202] Diseases of signal transduction by growth factor receptors and second messengers - v85:[updateContainedPathway] [UpdateTracker:9776620] Update Tracker - [Pathway:5663202] Diseases of signal transduction by growth factor receptors and second messengers - v75:[addHasEvent, updateContainedPathway] [UpdateTracker:9784604] Update Tracker - [Pathway:5663202] Diseases of signal transduction by growth factor receptors and second messengers - v53:[updateContainedPathway] [UpdateTracker:9783510] Update Tracker - [Pathway:5663202] Diseases of signal transduction by growth factor receptors and second messengers - v56:[updateContainedPathway] [UpdateTracker:9784039] Update Tracker - [Pathway:5663202] Diseases of signal transduction by growth factor receptors and second messengers - v55:[updateContainedPathway] [UpdateTracker:9776713] Update Tracker - [Pathway:5663202] Diseases of signal transduction by growth factor receptors and second messengers - v74:[updateContainedPathway] [UpdateTracker:9782832] Update Tracker - [Pathway:5663202] Diseases of signal transduction by growth factor receptors and second messengers - v58:[addHasEvent] [UpdateTracker:9864086] Update Tracker - [Pathway:5663202] Diseases of signal transduction by growth factor receptors and second messengers - v88:[addHasEvent] [UpdateTracker:9776135] Update Tracker - [Pathway:5663202] Diseases of signal transduction by growth factor receptors and second messengers - v77:[addHasEvent, updateContainedPathway] [UpdateTracker:9776927] Update Tracker - [Pathway:5663202] Diseases of signal transduction by growth factor receptors and second messengers - v73:[addHasEvent, updateContainedPathway] [UpdateTracker:9777185] Update Tracker - [Pathway:5663202] Diseases of signal transduction by growth factor receptors and second messengers - v72:[add_removeHasEvent, updateContainedPathway] [UpdateTracker:9775341] Update Tracker - [Pathway:5663202] Diseases of signal transduction by growth factor receptors and second messengers - v79:[updateContainedPathway] [UpdateTracker:9777425] Update Tracker - [Pathway:5663202] Diseases of signal transduction by growth factor receptors and second messengers - v71:[addHasEvent]

Referrals

(updatedInstance)

[UpdateTracker:9777590] Update Tracker - [Pathway:5663202] Diseases of signal transduction by growth factor receptors and second messengers - v70:[updateContainedPathway]
[UpdateTracker:9853268] Update Tracker - [Pathway:5663202] Diseases of signal transduction by growth factor receptors and second messengers - v87:[updateContainedPathway]
[UpdateTracker:9835723] Update Tracker - [Pathway:5663202] Diseases of signal transduction by growth factor receptors and second messengers - v85:[updateContainedPathway]
[UpdateTracker:9776620] Update Tracker - [Pathway:5663202] Diseases of signal transduction by growth factor receptors and second messengers - v75:[addHasEvent, updateContainedPathway]
[UpdateTracker:9784604] Update Tracker - [Pathway:5663202] Diseases of signal transduction by growth factor receptors and second messengers - v53:[updateContainedPathway]
[UpdateTracker:9783510] Update Tracker - [Pathway:5663202] Diseases of signal transduction by growth factor receptors and second messengers - v56:[updateContainedPathway]
[UpdateTracker:9784039] Update Tracker - [Pathway:5663202] Diseases of signal transduction by growth factor receptors and second messengers - v55:[updateContainedPathway]
[UpdateTracker:9776713] Update Tracker - [Pathway:5663202] Diseases of signal transduction by growth factor receptors and second messengers - v74:[updateContainedPathway]
[UpdateTracker:9782832] Update Tracker - [Pathway:5663202] Diseases of signal transduction by growth factor receptors and second messengers - v58:[addHasEvent]
[UpdateTracker:9864086] Update Tracker - [Pathway:5663202] Diseases of signal transduction by growth factor receptors and second messengers - v88:[addHasEvent]
[UpdateTracker:9776135] Update Tracker - [Pathway:5663202] Diseases of signal transduction by growth factor receptors and second messengers - v77:[addHasEvent, updateContainedPathway]
[UpdateTracker:9776927] Update Tracker - [Pathway:5663202] Diseases of signal transduction by growth factor receptors and second messengers - v73:[addHasEvent, updateContainedPathway]
[UpdateTracker:9777185] Update Tracker - [Pathway:5663202] Diseases of signal transduction by growth factor receptors and second messengers - v72:[add_removeHasEvent, updateContainedPathway]
[UpdateTracker:9775341] Update Tracker - [Pathway:5663202] Diseases of signal transduction by growth factor receptors and second messengers - v79:[updateContainedPathway]
[UpdateTracker:9777425] Update Tracker - [Pathway:5663202] Diseases of signal transduction by growth factor receptors and second messengers - v71:[addHasEvent]

(hasEvent)

[TopLevelPathway:R-HSA-1643685] Disease

Cite Us!