Reactome | Signaling by FGFR1

Schema > Pathway > Entries

Signaling by FGFR1 Show undefined attributes

authored	[InstanceEdit:190908] de Bono, B, 2007-01-10 10:27:18
created	[InstanceEdit:5654737] Rothfels, Karen, 2014-12-03
dbId	5654736
diseasePathways	[Pathway:R-HSA-5655302] Signaling by FGFR1 in disease - Homo sapiens
displayName	Signaling by FGFR1
doi	10.3180/R-HSA-5654736.3
edited	[InstanceEdit:193360] de Bono, B, D'Eustachio, P, 2007-02-10 20:21:22
eventOf	[Pathway:R-HSA-190236] Signaling by FGFR - Homo sapiens
figure	[Figure:1996286] /figures/Pathway_Illustrations/FGFR_72_oicr.png
goBiologicalProcess	[GO_BiologicalProcess:24611] fibroblast growth factor receptor signaling pathway
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-HSA-190242] FGFR1 ligand binding and activation - Homo sapiens [Pathway:R-HSA-5658623] FGFRL1 modulation of FGFR1 signaling - Homo sapiens [Pathway:R-HSA-5654687] Downstream signaling of activated FGFR1 - Homo sapiens [Pathway:R-HSA-5654726] Negative regulation of FGFR1 signaling - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2016-12-21
literatureReference	[LiteratureReference:190609] Cellular signaling by fibroblast growth factor receptors [LiteratureReference:190604] Common and distinct elements in cellular signaling via EGF and FGF receptors [LiteratureReference:190607] FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease [LiteratureReference:190605] Mechanisms underlying differential responses to FGF signaling [LiteratureReference:190251] Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family. [LiteratureReference:191444] Activation of the FGF receptor underlies neurite outgrowth stimulated by L1, N-CAM, and N-cadherin [LiteratureReference:1307936] Cell signaling by receptor tyrosine kinases [LiteratureReference:1307948] The FGF family: biology, pathophysiology and therapy
maxDepth	4
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	Signaling by FGFR1 Fibroblast Growth Factor Receptor (FGFR) signaling
orthologousEvent	[Pathway:R-SSC-5654736] Signaling by FGFR1 - Sus scrofa [Pathway:R-XTR-5654736] Signaling by FGFR1 - Xenopus tropicalis [Pathway:R-CEL-5654736] Signaling by FGFR1 - Caenorhabditis elegans [Pathway:R-GGA-5654736] Signaling by FGFR1 - Gallus gallus [Pathway:R-DME-5654736] Signaling by FGFR1 - Drosophila melanogaster [Pathway:R-DRE-5654736] Signaling by FGFR1 - Danio rerio [Pathway:R-BTA-5654736] Signaling by FGFR1 - Bos taurus [Pathway:R-CFA-5654736] Signaling by FGFR1 - Canis familiaris [Pathway:R-RNO-5654736] Signaling by FGFR1 - Rattus norvegicus [Pathway:R-MMU-5654736] Signaling by FGFR1 - Mus musculus
releaseDate	2007-02-20
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:192607] Mohammadi, M, 2007-02-06 21:44:35 [InstanceEdit:1549563] Gotoh, N, 2011-08-26 [InstanceEdit:8853855] Grose, Richard P, 2016-01-25
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-5654736
summation	[Summation:190610] The 22 members of the fibroblast growth factor (FGF) family ...
updateTrackers	[UpdateTracker:9783590] Update Tracker - [Pathway:5654736] Signaling by FGFR1 - v56:[addHasEvent, updateContainedPathway] [UpdateTracker:9783843] Update Tracker - [Pathway:5654736] Signaling by FGFR1 - v55:[removeHasEvent] [UpdateTracker:9784801] Update Tracker - [Pathway:5654736] Signaling by FGFR1 - v53:[updateContainedPathway] [UpdateTracker:9782944] Update Tracker - [Pathway:5654736] Signaling by FGFR1 - v58:[updateContainedPathway] [UpdateTracker:9782537] Update Tracker - [Pathway:5654736] Signaling by FGFR1 - v59:[updateContainedPathway]

Referrals

(updatedInstance)	[UpdateTracker:9783590] Update Tracker - [Pathway:5654736] Signaling by FGFR1 - v56:[addHasEvent, updateContainedPathway] [UpdateTracker:9783843] Update Tracker - [Pathway:5654736] Signaling by FGFR1 - v55:[removeHasEvent] [UpdateTracker:9784801] Update Tracker - [Pathway:5654736] Signaling by FGFR1 - v53:[updateContainedPathway] [UpdateTracker:9782944] Update Tracker - [Pathway:5654736] Signaling by FGFR1 - v58:[updateContainedPathway] [UpdateTracker:9782537] Update Tracker - [Pathway:5654736] Signaling by FGFR1 - v59:[updateContainedPathway]
(hasEncapsulatedEvent)	[Pathway:R-HSA-9839373] Signaling by TGFBR3 [Pathway:R-HSA-5673001] RAF/MAP kinase cascade
(normalPathway)	[Pathway:R-HSA-5655302] Signaling by FGFR1 in disease
(hasEvent)	[Pathway:R-HSA-190236] Signaling by FGFR

Cite Us!