Reactome | FGFR1 ligand binding and activation

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FGFR1 ligand binding and activation Show undefined attributes

authored	[InstanceEdit:190908] de Bono, B, 2007-01-10 10:27:18
created	[InstanceEdit:190238] de Bono, B, 2006-12-18 14:16:28
dbId	190242
displayName	FGFR1 ligand binding and activation
edited	[InstanceEdit:193360] de Bono, B, D'Eustachio, P, 2007-02-10 20:21:22
eventOf	[Pathway:R-HSA-5654736] Signaling by FGFR1 - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:24611] fibroblast growth factor receptor signaling pathway
hasDiagram	false
hasEHLD	false
hasEvent	[Pathway:R-HSA-190370] FGFR1b ligand binding and activation - Homo sapiens [Pathway:R-HSA-190373] FGFR1c ligand binding and activation - Homo sapiens [Pathway:R-HSA-190374] FGFR1c and Klotho ligand binding and activation - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2023-09-13
literatureReference	[LiteratureReference:190912] The structure and function of vertebrate fibroblast growth factor receptor 1 [LiteratureReference:190986] Structural basis for a direct interaction between FGFR1 and NCAM and evidence for a regulatory role of ATP [LiteratureReference:190995] Structural biology of NCAM homophilic binding and activation of FGFR [LiteratureReference:190251] Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family.
maxDepth	3
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	FGFR1 ligand binding and activation
orthologousEvent	[Pathway:R-SSC-190242] FGFR1 ligand binding and activation - Sus scrofa [Pathway:R-CEL-190242] FGFR1 ligand binding and activation - Caenorhabditis elegans [Pathway:R-DME-190242] FGFR1 ligand binding and activation - Drosophila melanogaster [Pathway:R-GGA-190242] FGFR1 ligand binding and activation - Gallus gallus [Pathway:R-XTR-190242] FGFR1 ligand binding and activation - Xenopus tropicalis [Pathway:R-DRE-190242] FGFR1 ligand binding and activation - Danio rerio [Pathway:R-BTA-190242] FGFR1 ligand binding and activation - Bos taurus [Pathway:R-CFA-190242] FGFR1 ligand binding and activation - Canis familiaris [Pathway:R-RNO-190242] FGFR1 ligand binding and activation - Rattus norvegicus [Pathway:R-MMU-190242] FGFR1 ligand binding and activation - Mus musculus
releaseDate	2007-02-20
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:192607] Mohammadi, M, 2007-02-06 21:44:35 [InstanceEdit:8851378] Grose, Richard P, 2016-01-06
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-190242
summation	[Summation:190969] The vertebrate fibroblast growth factor receptor 1 (FGFR1) i...
updateTrackers	[UpdateTracker:9788921] Update Tracker - [Pathway:190242] FGFR1 ligand binding and activation - v39:[updateIndirectRLE] [UpdateTracker:9785426] Update Tracker - [Pathway:190242] FGFR1 ligand binding and activation - v52:[addHasEvent, updateIndirectRLE] [UpdateTracker:9842269] Update Tracker - [Pathway:190242] FGFR1 ligand binding and activation - v86:[updateIndirectRLE] [UpdateTracker:9783365] Update Tracker - [Pathway:190242] FGFR1 ligand binding and activation - v56:[updateContainedPathway] [UpdateTracker:9790931] Update Tracker - [Pathway:190242] FGFR1 ligand binding and activation - v32:[updateIndirectRLE] [UpdateTracker:9792357] Update Tracker - [Pathway:190242] FGFR1 ligand binding and activation - v22:[updateIndirectRLE] [UpdateTracker:9789697] Update Tracker - [Pathway:190242] FGFR1 ligand binding and activation - v37:[addLiteratureReference, removeHasEvent, updateContainedPathway, updateIndirectRLE] [UpdateTracker:9786533] Update Tracker - [Pathway:190242] FGFR1 ligand binding and activation - v49:[modifyText]

Referrals

(updatedInstance)

[UpdateTracker:9788921] Update Tracker - [Pathway:190242] FGFR1 ligand binding and activation - v39:[updateIndirectRLE]
[UpdateTracker:9785426] Update Tracker - [Pathway:190242] FGFR1 ligand binding and activation - v52:[addHasEvent, updateIndirectRLE]
[UpdateTracker:9842269] Update Tracker - [Pathway:190242] FGFR1 ligand binding and activation - v86:[updateIndirectRLE]
[UpdateTracker:9783365] Update Tracker - [Pathway:190242] FGFR1 ligand binding and activation - v56:[updateContainedPathway]
[UpdateTracker:9790931] Update Tracker - [Pathway:190242] FGFR1 ligand binding and activation - v32:[updateIndirectRLE]
[UpdateTracker:9792357] Update Tracker - [Pathway:190242] FGFR1 ligand binding and activation - v22:[updateIndirectRLE]
[UpdateTracker:9789697] Update Tracker - [Pathway:190242] FGFR1 ligand binding and activation - v37:[addLiteratureReference, removeHasEvent, updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9786533] Update Tracker - [Pathway:190242] FGFR1 ligand binding and activation - v49:[modifyText]

(hasEvent)

[Pathway:R-HSA-5654736] Signaling by FGFR1

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