Reactome | Signaling by FGFR

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Signaling by FGFR Show undefined attributes

authored	[InstanceEdit:190908] de Bono, B, 2007-01-10 10:27:18
created	[InstanceEdit:190237] de Bono, B, 2006-12-18 14:14:02
dbId	190236
displayName	Signaling by FGFR
doi	10.3180/REACT_9470.9
edited	[InstanceEdit:193360] de Bono, B, D'Eustachio, P, 2007-02-10 20:21:22
eventOf	[Pathway:R-HSA-9006934] Signaling by Receptor Tyrosine Kinases - Homo sapiens
figure	[Figure:9628952] /figures/ehld/R-HSA-190236.svg
goBiologicalProcess	[GO_BiologicalProcess:24611] fibroblast growth factor receptor signaling pathway
hasDiagram	true
hasEHLD	true
hasEvent	[Pathway:R-HSA-5654736] Signaling by FGFR1 - Homo sapiens [Pathway:R-HSA-5654738] Signaling by FGFR2 - Homo sapiens [Pathway:R-HSA-5654741] Signaling by FGFR3 - Homo sapiens [Pathway:R-HSA-5654743] Signaling by FGFR4 - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2016-03-24
literatureReference	[LiteratureReference:190609] Cellular signaling by fibroblast growth factor receptors [LiteratureReference:190604] Common and distinct elements in cellular signaling via EGF and FGF receptors [LiteratureReference:190607] FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease [LiteratureReference:190605] Mechanisms underlying differential responses to FGF signaling [LiteratureReference:190251] Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family. [LiteratureReference:191444] Activation of the FGF receptor underlies neurite outgrowth stimulated by L1, N-CAM, and N-cadherin [LiteratureReference:1307936] Cell signaling by receptor tyrosine kinases [LiteratureReference:1307948] The FGF family: biology, pathophysiology and therapy
maxDepth	5
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	Signaling by FGFR Fibroblast Growth Factor Receptor (FGFR) signaling
orthologousEvent	[Pathway:R-SSC-190236] Signaling by FGFR - Sus scrofa [Pathway:R-CEL-190236] Signaling by FGFR - Caenorhabditis elegans [Pathway:R-DME-190236] Signaling by FGFR - Drosophila melanogaster [Pathway:R-GGA-190236] Signaling by FGFR - Gallus gallus [Pathway:R-XTR-190236] Signaling by FGFR - Xenopus tropicalis [Pathway:R-DRE-190236] Signaling by FGFR - Danio rerio [Pathway:R-BTA-190236] Signaling by FGFR - Bos taurus [Pathway:R-CFA-190236] Signaling by FGFR - Canis familiaris [Pathway:R-RNO-190236] Signaling by FGFR - Rattus norvegicus [Pathway:R-MMU-190236] Signaling by FGFR - Mus musculus
releaseDate	2007-02-20
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:192607] Mohammadi, M, 2007-02-06 21:44:35 [InstanceEdit:1549563] Gotoh, N, 2011-08-26
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-190236
summation	[Summation:190610] The 22 members of the fibroblast growth factor (FGF) family ...
updateTrackers	[UpdateTracker:9786397] Update Tracker - [Pathway:190236] Signaling by FGFR - v49:[updateContainedPathway] [UpdateTracker:9783863] Update Tracker - [Pathway:190236] Signaling by FGFR - v55:[updateContainedPathway] [UpdateTracker:9783726] Update Tracker - [Pathway:190236] Signaling by FGFR - v56:[updateContainedPathway] [UpdateTracker:9789486] Update Tracker - [Pathway:190236] Signaling by FGFR - v38:[addHasEvent, updateContainedPathway] [UpdateTracker:9789787] Update Tracker - [Pathway:190236] Signaling by FGFR - v37:[addLiteratureReference, modifyText, updateContainedPathway] [UpdateTracker:9790843] Update Tracker - [Pathway:190236] Signaling by FGFR - v32:[addHasEvent] [UpdateTracker:9785119] Update Tracker - [Pathway:190236] Signaling by FGFR - v52:[add_removeHasEvent]

Referrals

(updatedInstance)	[UpdateTracker:9786397] Update Tracker - [Pathway:190236] Signaling by FGFR - v49:[updateContainedPathway] [UpdateTracker:9783863] Update Tracker - [Pathway:190236] Signaling by FGFR - v55:[updateContainedPathway] [UpdateTracker:9783726] Update Tracker - [Pathway:190236] Signaling by FGFR - v56:[updateContainedPathway] [UpdateTracker:9789486] Update Tracker - [Pathway:190236] Signaling by FGFR - v38:[addHasEvent, updateContainedPathway] [UpdateTracker:9789787] Update Tracker - [Pathway:190236] Signaling by FGFR - v37:[addLiteratureReference, modifyText, updateContainedPathway] [UpdateTracker:9790843] Update Tracker - [Pathway:190236] Signaling by FGFR - v32:[addHasEvent] [UpdateTracker:9785119] Update Tracker - [Pathway:190236] Signaling by FGFR - v52:[add_removeHasEvent]
(hasEvent)	[Pathway:R-HSA-9006934] Signaling by Receptor Tyrosine Kinases
(hasEncapsulatedEvent)	[Pathway:R-HSA-1257604] PIP3 activates AKT signaling

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