Reactome | Activated FGFR3:p-FRS:GRB2:SOS1 [plasma membrane]

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Activated FGFR3:p-FRS:GRB2:SOS1 [plasma membrane] Show undefined attributes

catalystActivities	[CatalystActivity:5654415] guanyl-nucleotide exchange factor activity of Activated FGFR3:p-FRS:GRB2:SOS1 [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:5654309] Rothfels, Karen, 2014-12-03
dbId	5654308
displayName	Activated FGFR3:p-FRS:GRB2:SOS1 [plasma membrane]
hasComponent	[DefinedSet:R-HSA-5654305] Activated FGFR3:p-FRS [plasma membrane] [Complex:R-HSA-109797] GRB2-1:SOS1 [cytosol]
inDisease	false
includedLocation	[Compartment:70101] cytosol
inferredTo	[Complex:R-MMU-5654308] Activated FGFR3:p-FRS:GRB2:SOS1 [plasma membrane] - Mus musculus [Complex:R-RNO-5654308] Activated FGFR3:p-FRS:GRB2:SOS1 [plasma membrane] - Rattus norvegicus [Complex:R-CFA-5654308] Activated FGFR3:p-FRS:GRB2:SOS1 [plasma membrane] - Canis familiaris [Complex:R-BTA-5654308] Activated FGFR3:p-FRS:GRB2:SOS1 [plasma membrane] - Bos taurus [Complex:R-SSC-5654308] Activated FGFR3:p-FRS:GRB2:SOS1 [plasma membrane] - Sus scrofa [Complex:R-DRE-5654308] Activated FGFR3:p-FRS:GRB2:SOS1 [plasma membrane] - Danio rerio [Complex:R-XTR-5654308] Activated FGFR3:p-FRS:GRB2:SOS1 [plasma membrane] - Xenopus tropicalis [Complex:R-GGA-5654308] Activated FGFR3:p-FRS:GRB2:SOS1 [plasma membrane] - Gallus gallus [Complex:R-DME-5654308] Activated FGFR3:p-FRS:GRB2:SOS1 [plasma membrane] - Drosophila melanogaster [Complex:R-CEL-5654308] Activated FGFR3:p-FRS:GRB2:SOS1 [plasma membrane] - Caenorhabditis elegans
isChimeric	false
maxDepth	7
memberOf	[DefinedSet:R-HSA-5672601] RAS GEFs [plasma membrane] - Homo sapiens
name	Activated FGFR3:p-FRS:GRB2:SOS1
producedByEvent	[Reaction:R-HSA-5654416] Activated FGFR3:pFRS binds GRB2:SOS1 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-5654308
updateTrackers	[UpdateTracker:9898372] Update Tracker - [Complex:5654308] Activated FGFR3:p-FRS:GRB2:SOS1 [plasma membrane] - v63:[updateContainedComponent] [UpdateTracker:9892566] Update Tracker - [Complex:5654308] Activated FGFR3:p-FRS:GRB2:SOS1 [plasma membrane] - v53:[updateContainedComponent] [UpdateTracker:9894190] Update Tracker - [Complex:5654308] Activated FGFR3:p-FRS:GRB2:SOS1 [plasma membrane] - v56:[updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9898372] Update Tracker - [Complex:5654308] Activated FGFR3:p-FRS:GRB2:SOS1 [plasma membrane] - v63:[updateContainedComponent] [UpdateTracker:9892566] Update Tracker - [Complex:5654308] Activated FGFR3:p-FRS:GRB2:SOS1 [plasma membrane] - v53:[updateContainedComponent] [UpdateTracker:9894190] Update Tracker - [Complex:5654308] Activated FGFR3:p-FRS:GRB2:SOS1 [plasma membrane] - v56:[updateContainedComponent]
(normalEntity)	[EntityFunctionalStatus:5655261] gain_of_function of FGFR3 point, translocation and fusion mutants:p-FRS2:GRB2:SOS1 [plasma membrane]
(physicalEntity)	[CatalystActivity:5654415] guanyl-nucleotide exchange factor activity of Activated FGFR3:p-FRS:GRB2:SOS1 [plasma membrane]
(output)	[Reaction:R-HSA-5654416] Activated FGFR3:pFRS binds GRB2:SOS1
(hasMember)	[DefinedSet:R-HSA-5672601] RAS GEFs [plasma membrane]

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