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Activated FGFR3:p-FRS:GRB2:SOS1 [plasma membrane]
Stable Identifier
R-HSA-5654308
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
MAPK family signaling cascades (Homo sapiens)
MAPK1/MAPK3 signaling (Homo sapiens)
RAF/MAP kinase cascade (Homo sapiens)
RAS GEFs promote RAS nucleotide exchange (Homo sapiens)
RAS GEFs [plasma membrane] (Homo sapiens)
Activated FGFR3:p-FRS:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by FGFR (Homo sapiens)
Signaling by FGFR3 (Homo sapiens)
Downstream signaling of activated FGFR3 (Homo sapiens)
FRS-mediated FGFR3 signaling (Homo sapiens)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)
Activated FGFR3:p-FRS:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Activated FGFR3:pFRS binds GRB2:SOS1 (Homo sapiens)
Activated FGFR3:p-FRS:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Participants
components
Activated FGFR3:p-FRS [plasma membrane] (Homo sapiens)
GRB2-1:SOS1 [cytosol] (Homo sapiens)
Participant Of
output
Activated FGFR3:pFRS binds GRB2:SOS1
hasMember
RAS GEFs [plasma membrane]
Inferred To
Activated FGFR3:p-FRS:GRB2:SOS1 [plasma membrane] (Bos taurus)
Activated FGFR3:p-FRS:GRB2:SOS1 [plasma membrane] (Caenorhabditis elegans)
Activated FGFR3:p-FRS:GRB2:SOS1 [plasma membrane] (Canis familiaris)
Activated FGFR3:p-FRS:GRB2:SOS1 [plasma membrane] (Danio rerio)
Activated FGFR3:p-FRS:GRB2:SOS1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR3:p-FRS:GRB2:SOS1 [plasma membrane] (Gallus gallus)
Activated FGFR3:p-FRS:GRB2:SOS1 [plasma membrane] (Mus musculus)
Activated FGFR3:p-FRS:GRB2:SOS1 [plasma membrane] (Rattus norvegicus)
Activated FGFR3:p-FRS:GRB2:SOS1 [plasma membrane] (Sus scrofa)
Activated FGFR3:p-FRS:GRB2:SOS1 [plasma membrane] (Xenopus tropicalis)
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