Reactome | Activated FGFR3 [plasma membrane]

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Activated FGFR3 [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-5654300] Activated FGFR3:SHC1 [plasma membrane] - Homo sapiens [Complex:R-HSA-5654226] activated FGFR3:PLCG1 [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-5654625] Activated FGFR3 binds SHC1 - Homo sapiens [Reaction:R-HSA-5654224] Activated FGFR3 binds PLCG1 - Homo sapiens [Reaction:R-HSA-5654409] Activated FGFR3 binds FRS2 - Homo sapiens [Reaction:R-HSA-5654623] Activated FGFR3 binds FRS3 - Homo sapiens
created	[InstanceEdit:5654153] Rothfels, Karen, 2014-12-03
dbId	5654146
displayName	Activated FGFR3 [plasma membrane]
hasMember	[Complex:R-HSA-190380] Activated FGFR3b homodimer [plasma membrane] - Homo sapiens [Complex:R-HSA-190389] Activated FGFR3c homodimer [plasma membrane] - Homo sapiens
inDisease	false
inferredTo	[DefinedSet:R-MMU-5654146] Activated FGFR3 [plasma membrane] - Mus musculus [DefinedSet:R-RNO-5654146] Activated FGFR3 [plasma membrane] - Rattus norvegicus [DefinedSet:R-CFA-5654146] Activated FGFR3 [plasma membrane] - Canis familiaris [DefinedSet:R-BTA-5654146] Activated FGFR3 [plasma membrane] - Bos taurus [GenomeEncodedEntity:R-SSC-5654146] Ghost homologue of Activated FGFR3 [plasma membrane] - Sus scrofa [DefinedSet:R-DRE-5654146] Activated FGFR3 [plasma membrane] - Danio rerio [DefinedSet:R-XTR-5654146] Activated FGFR3 [plasma membrane] - Xenopus tropicalis [DefinedSet:R-GGA-5654146] Activated FGFR3 [plasma membrane] - Gallus gallus [DefinedSet:R-DME-5654146] Activated FGFR3 [plasma membrane] - Drosophila melanogaster [DefinedSet:R-CEL-5654146] Activated FGFR3 [plasma membrane] - Caenorhabditis elegans
maxDepth	4
modified	[InstanceEdit:5674037] Rothfels, Karen, 2015-02-10
name	Activated FGFR3
producedByEvent	[Reaction:R-HSA-5654148] p-4Y-PLCG1 dissociates from activated FGFR3 - Homo sapiens
schemaClass	DefinedSet
species	[Species:48887] Homo sapiens
stId	R-HSA-5654146
updateTrackers	[UpdateTracker:9893421] Update Tracker - [DefinedSet:5654146] Activated FGFR3 [plasma membrane] - v56:[updateContainedMemberOrCandidate]

Referrals

(updatedInstance)	[UpdateTracker:9893421] Update Tracker - [DefinedSet:5654146] Activated FGFR3 [plasma membrane] - v56:[updateContainedMemberOrCandidate]
(normalEntity)	[EntityFunctionalStatus:9757294] gain_of_function of Activated FGFR3 point and translocation mutants [plasma membrane] [EntityFunctionalStatus:5655276] gain_of_function of Activated FGFR3 point, translocation and fusion mutants [plasma membrane]
(input)	[Reaction:R-HSA-5654625] Activated FGFR3 binds SHC1 [Reaction:R-HSA-5654224] Activated FGFR3 binds PLCG1 [Reaction:R-HSA-5654409] Activated FGFR3 binds FRS2 [Reaction:R-HSA-5654623] Activated FGFR3 binds FRS3
(hasComponent)	[Complex:R-HSA-5654300] Activated FGFR3:SHC1 [plasma membrane] [Complex:R-HSA-5654226] activated FGFR3:PLCG1 [plasma membrane] [Complex:R-HSA-5654156] activated FGFR3:p-4Y-PLCG1 [plasma membrane] [Complex:R-HSA-5654314] Activated FGFR3:pY-SHC1 [plasma membrane] [Complex:R-HSA-5654301] Activated FGFR3:p-8T-FRS2 [plasma membrane] [Complex:R-HSA-5654180] Activated FGFR3:FRS2 [plasma membrane] [Complex:R-HSA-5654297] Activated FGFR3:FRS3 [plasma membrane] [Complex:R-HSA-5654303] Activated FGFR3:p-FRS3 [plasma membrane] [Complex:R-HSA-5654196] Activated FGFR3:p-FRS2 [plasma membrane]
(output)	[Reaction:R-HSA-5654148] p-4Y-PLCG1 dissociates from activated FGFR3

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