Reactome | Activated FGFR4 [plasma membrane]

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Activated FGFR4 [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-5654319] Activated FGFR4:FRS3 [plasma membrane] - Homo sapiens [Complex:R-HSA-5654166] activated FGFR4:PLCG1 [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-5654651] Activated FGFR4 binds FRS3 - Homo sapiens [Reaction:R-HSA-5654422] Activated FGFR4 binds FRS2 - Homo sapiens [Reaction:R-HSA-5654163] Activated FGFR4 binds PLCG1 - Homo sapiens [Reaction:R-HSA-5654425] Activated FGFR4 binds SHC1 - Homo sapiens
created	[InstanceEdit:5654153] Rothfels, Karen, 2014-12-03
dbId	5654158
displayName	Activated FGFR4 [plasma membrane]
hasMember	[Complex:R-HSA-190328] Activated FGFR4 homodimer [plasma membrane] - Homo sapiens [Complex:R-HSA-1307958] Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] - Homo sapiens
inDisease	false
inferredTo	[DefinedSet:R-MMU-5654158] Activated FGFR4 [plasma membrane] - Mus musculus [DefinedSet:R-RNO-5654158] Activated FGFR4 [plasma membrane] - Rattus norvegicus [DefinedSet:R-CFA-5654158] Activated FGFR4 [plasma membrane] - Canis familiaris [DefinedSet:R-BTA-5654158] Activated FGFR4 [plasma membrane] - Bos taurus [DefinedSet:R-SSC-5654158] Activated FGFR4 [plasma membrane] - Sus scrofa [DefinedSet:R-DRE-5654158] Activated FGFR4 [plasma membrane] - Danio rerio [DefinedSet:R-XTR-5654158] Activated FGFR4 [plasma membrane] - Xenopus tropicalis [DefinedSet:R-GGA-5654158] Activated FGFR4 [plasma membrane] - Gallus gallus [DefinedSet:R-DME-5654158] Activated FGFR4 [plasma membrane] - Drosophila melanogaster [Complex:R-CEL-190328] Activated FGFR4 homodimer [plasma membrane] - Caenorhabditis elegans
maxDepth	4
name	Activated FGFR4
producedByEvent	[Reaction:R-HSA-5654169] p-4Y-PLCG1 dissociates from activated FGFR4 - Homo sapiens
schemaClass	DefinedSet
species	[Species:48887] Homo sapiens
stId	R-HSA-5654158
updateTrackers	[UpdateTracker:9893898] Update Tracker - [DefinedSet:5654158] Activated FGFR4 [plasma membrane] - v56:[updateContainedMemberOrCandidate]

Referrals

(updatedInstance)	[UpdateTracker:9893898] Update Tracker - [DefinedSet:5654158] Activated FGFR4 [plasma membrane] - v56:[updateContainedMemberOrCandidate]
(normalEntity)	[EntityFunctionalStatus:5655335] gain_of_function of Activated FGFR4 mutants [plasma membrane]
(hasComponent)	[Complex:R-HSA-5654319] Activated FGFR4:FRS3 [plasma membrane] [Complex:R-HSA-5654322] Activated FGFR4:p-8T-FRS2 [plasma membrane] [Complex:R-HSA-5654182] Activated FGFR4:FRS2 [plasma membrane] [Complex:R-HSA-5654166] activated FGFR4:PLCG1 [plasma membrane] [Complex:R-HSA-5654168] activated FGFR4:p-4Y-PLCG1 [plasma membrane] [Complex:R-HSA-5654320] Activated FGFR4:SHC1 [plasma membrane] [Complex:R-HSA-5654326] Activated FGFR4:p-FRS3 [plasma membrane] [Complex:R-HSA-5654340] Activated FGFR4:pY-SHC1 [plasma membrane] [Complex:R-HSA-5654193] Activated FGFR4:p-FRS2 [plasma membrane]
(input)	[Reaction:R-HSA-5654651] Activated FGFR4 binds FRS3 [Reaction:R-HSA-5654422] Activated FGFR4 binds FRS2 [Reaction:R-HSA-5654163] Activated FGFR4 binds PLCG1 [Reaction:R-HSA-5654425] Activated FGFR4 binds SHC1
(output)	[Reaction:R-HSA-5654169] p-4Y-PLCG1 dissociates from activated FGFR4

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