Reactome | p-4Y-PLCG1 dissociates from activated FGFR4

Schema > Reaction > Entries

p-4Y-PLCG1 dissociates from activated FGFR4 Show undefined attributes

authored	[InstanceEdit:190908] de Bono, B, 2007-01-10 10:27:18
category	dissociation
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:5654153] Rothfels, Karen, 2014-12-03
dbId	5654169
deleted	[Deleted:5655553] Deletion of instance: 190905
diseaseReaction	[Reaction:R-HSA-5655336] p-4Y-PLCG1 dissociates from activated FGFR4 mutants - Homo sapiens
displayName	p-4Y-PLCG1 dissociates from activated FGFR4
edited	[InstanceEdit:500337] Jupe, S, 2010-02-03
eventOf	[Pathway:R-HSA-5654228] Phospholipase C-mediated cascade; FGFR4 - Homo sapiens
followingEvent	[Reaction:R-HSA-167686] Active PLCG1 hydrolyses PIP2 - Homo sapiens
input	[Complex:R-HSA-5654168] activated FGFR4:p-4Y-PLCG1 [plasma membrane]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:189824] Phospholipase C-gamma as a signal-transducing element
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	p-4Y-PLCG1 dissociates from activated FGFR4
orthologousEvent	[Reaction:R-CEL-5654169] p-4Y-PLCG1 dissociates from activated FGFR4 - Caenorhabditis elegans [Reaction:R-DME-5654169] p-4Y-PLCG1 dissociates from activated FGFR4 - Drosophila melanogaster [Reaction:R-GGA-5654169] p-4Y-PLCG1 dissociates from activated FGFR4 - Gallus gallus [Reaction:R-XTR-5654169] p-4Y-PLCG1 dissociates from activated FGFR4 - Xenopus tropicalis [Reaction:R-DRE-5654169] p-4Y-PLCG1 dissociates from activated FGFR4 - Danio rerio [Reaction:R-SSC-5654169] p-4Y-PLCG1 dissociates from activated FGFR4 - Sus scrofa [Reaction:R-BTA-5654169] p-4Y-PLCG1 dissociates from activated FGFR4 - Bos taurus [Reaction:R-CFA-5654169] p-4Y-PLCG1 dissociates from activated FGFR4 - Canis familiaris [Reaction:R-RNO-5654169] p-4Y-PLCG1 dissociates from activated FGFR4 - Rattus norvegicus [Reaction:R-MMU-5654169] p-4Y-PLCG1 dissociates from activated FGFR4 - Mus musculus
output	[DefinedSet:R-HSA-5654158] Activated FGFR4 [plasma membrane] [EntityWithAccessionedSequence:R-HSA-167679] p-4Y-PLCG1 [plasma membrane]
precedingEvent	[Reaction:R-HSA-5654151] Activated FGFR4 phosphorylates PLCG1 - Homo sapiens
releaseDate	2010-03-16
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:192607] Mohammadi, M, 2007-02-06 21:44:35
revised	[InstanceEdit:5654034] Rothfels, Karen, 2014-12-03
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-5654169
summation	[Summation:191520] Dissociation from the activated receptor quickly follows pho...

Referrals

(replacementInstances)	[Deleted:5655553] Deletion of instance: 190905
(normalReaction)	[Reaction:R-HSA-5655336] p-4Y-PLCG1 dissociates from activated FGFR4 mutants
(hasEvent)	[Pathway:R-HSA-5654228] Phospholipase C-mediated cascade; FGFR4
(precedingEvent)	[Reaction:R-HSA-167686] Active PLCG1 hydrolyses PIP2