Reactome | LIG1, APEX1 and PCNA:POLD,POLE:RPA:RFC dissociate from repaired DNA

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LIG1, APEX1 and PCNA:POLD,POLE:RPA:RFC dissociate from repaired DNA Show undefined attributes

authored	[InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03
category	dissociation
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:5651806] Orlic-Milacic, Marija, 2014-11-24
dbId	5651809
displayName	LIG1, APEX1 and PCNA:POLD,POLE:RPA:RFC dissociate from repaired DNA
edited	[InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03 [InstanceEdit:110568] Matthews, L, 2004-02-03 00:30:00
eventOf	[Pathway:R-HSA-5651801] PCNA-Dependent Long Patch Base Excision Repair - Homo sapiens
input	[Complex:R-HSA-5651810] LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:dsDNA [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:111248] Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1). [LiteratureReference:111254] AP endonuclease 1 coordinates flap endonuclease 1 and DNA ligase I activity in long patch base excision repair. [LiteratureReference:5358859] Mechanism underlying replication protein a stimulation of DNA ligase I
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	LIG1, APEX1 and PCNA:POLD,POLE:RPA:RFC dissociate from repaired DNA
output	[EntityWithAccessionedSequence:R-HSA-50119] APEX1 [nucleoplasm] [GenomeEncodedEntity:R-HSA-5649637] dsDNA [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-53787] LIG1 [nucleoplasm] [Complex:R-HSA-5651799] PCNA:POLD,POLE:RPA:RFC [nucleoplasm]
precedingEvent	[Reaction:R-HSA-5651805] LIG1 bound to APEX1 and PCNA ligates SSB - Homo sapiens
releaseDate	2004-03-06
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5673689] Borowiec, James, 2014-12-22
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-5651809
summation	[Summation:5651908] After the PCNA-dependent long patch base excision (BER) is c...

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(hasEvent)

[Pathway:R-HSA-5651801] PCNA-Dependent Long Patch Base Excision Repair

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