Reactome | Me2K21-HIST1H4 [nucleoplasm]

Schema > EntityWithAccessionedSequence > Entries

Me2K21-HIST1H4 [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-5682998] K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] - Homo sapiens [Complex:R-HSA-5682998] K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] - Homo sapiens [Complex:R-HSA-9749196] H4K20Me2-nucleosome [nucleoplasm] - Homo sapiens [Complex:R-HSA-9749196] H4K20Me2-nucleosome [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-5651657] SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) - Homo sapiens
created	[InstanceEdit:5651644] Jupe, Steve, 2014-11-24
dbId	5651652
displayName	Me2K21-HIST1H4 [nucleoplasm]
endCoordinate	103
hasModifiedResidue	[ModifiedResidue:5651658] N6,N6-dimethyl-L-lysine at 21
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-5651652] H4c11 [nucleoplasm] - Mus musculus [EntityWithAccessionedSequence:R-RNO-5651652] H4c16 [nucleoplasm] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-5651652] LOC119867697 [nucleoplasm] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-5651652] Me2K21-HIST1H4 [nucleoplasm] - Bos taurus [EntityWithAccessionedSequence:R-SSC-5651652] Me2K21-HIST1H4 [nucleoplasm] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-5651652] si:ch1073-159d7.2 [nucleoplasm] - Danio rerio [EntityWithAccessionedSequence:R-XTR-5651652] h4c3 [nucleoplasm] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-5651652] H4-VI [nucleoplasm] - Gallus gallus [EntityWithAccessionedSequence:R-DME-5651652] His4:CG33889 [nucleoplasm] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-5651652] his-56 [nucleoplasm] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-DDI-5651652] H4b [nucleoplasm] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-SPO-5651652] hhf3 [nucleoplasm] - Schizosaccharomyces pombe [EntityWithAccessionedSequence:R-SCE-5651652] HHF2 [nucleoplasm] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-PFA-5651652] Me2K21-HIST1H4 [nucleoplasm] - Plasmodium falciparum
maxDepth	1
name	Me2K21-HIST1H4 Histone H4 HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H4A HIST2H4B
producedByEvent	[Reaction:R-HSA-5651654] SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:P62805] UniProt:P62805 H4C1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-5651652
startCoordinate	2

Referrals

(input)	[Reaction:R-HSA-5651657] SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20)
(output)	[Reaction:R-HSA-5651654] SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20)
(hasComponent)	[Complex:R-HSA-9749196] H4K20Me2-nucleosome [nucleoplasm] [Complex:R-HSA-5682998] K63PolyUb:K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm] [Complex:R-HSA-5682971] p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome [nucleoplasm]
(activeUnit)	[PositiveRegulation:9749193] Positive regulation by 'ORC1:H4K20Me2-nucleosome'

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